Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NT5E | P21589 | 1/20 | 0.36 |
| ▸ | TYMP | P19971 | 1/20 | 0.35 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.34 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.34 |
| ▸ | GHSR | Q92847 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | DUT | P33316 | 5/20 | 0.33 |
| ▸ | SLC6A1 | P30531 | 2/20 | 0.33 |
| ▸ | SLC6A11 | P48066 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4075035 | 0.88 | NT5E (0.40) | NT5ETYMPP2RY6P2RY14DUT | |
| SCHEMBL4083482 | 0.84 | P2RY6 (0.39) | NT5ETYMPP2RY6P2RY14ALDH1A1 | |
| SCHEMBL13722156 | 0.84 | NT5E (0.39) | NT5EP2RY6P2RY14 | |
| SCHEMBL1098282 | 0.83 | P2RY6 (0.38) | NT5ETYMPP2RY6P2RY14DUT | |
| SCHEMBL4074748 | 0.83 | P2RY6 (0.38) | NT5ETYMPP2RY6P2RY14DUT | |
| SCHEMBL13722164 | 0.83 | NT5E (0.39) | NT5EP2RY6P2RY14DUT | |
| SCHEMBL4078638 | 0.82 | NT5E (0.38) | NT5EP2RY14GHSRMAPK1DUT | |
| SCHEMBL4078632 | 0.82 | NT5E (0.40) | NT5EP2RY6P2RY14GHSRMAPK1 | |
| SCHEMBL13721986 | 0.81 | NT5E (0.39) | NT5EP2RY6P2RY14DUT | |
| SCHEMBL1096814 | 0.79 | P2RY6 (0.38) | NT5ETYMPP2RY6P2RY14DUT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7569686-B1 | Compounds and methods for synthesis of bicyclic nucleic acid analogs | ISIS PHARMACEUTICALS, INC. (US) | 2009-08-04 | — | — | US | disclosed |