Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY6 | Q15077 | 3/20 | 0.38 |
| ▸ | P2RY14 | Q15391 | 2/20 | 0.38 |
| ▸ | TYMP | P19971 | 1/20 | 0.38 |
| ▸ | NT5E | P21589 | 1/20 | 0.37 |
| ▸ | DUT | P33316 | 5/20 | 0.37 |
| ▸ | SLC6A1 | P30531 | 2/20 | 0.35 |
| ▸ | SLC6A11 | P48066 | 1/20 | 0.35 |
| ▸ | P2RY2 | P41231 | 2/20 | 0.34 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.34 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.34 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.34 |
| ▸ | SLC28A3 | Q9HAS3 | 1/20 | 0.34 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1098282 | 1.00 | P2RY6 (0.38) | P2RY6P2RY14TYMPNT5EDUT | |
| SCHEMBL7096692 | 0.89 | P2RY6 (0.41) | P2RY6P2RY14TYMPNT5EDUT | |
| SCHEMBL12386210 | 0.89 | P2RY6 (0.41) | P2RY6P2RY14TYMPNT5EDUT | |
| SCHEMBL4075035 | 0.89 | NT5E (0.40) | P2RY6P2RY14TYMPNT5EDUT | |
| SCHEMBL24512779 | 0.87 | TK2 (0.42) | — | |
| SCHEMBL5557408 | 0.87 | TK2 (0.42) | — | |
| SCHEMBL5582060 | 0.87 | TK2 (0.42) | — | |
| SCHEMBL2769235 | 0.87 | TK2 (0.42) | — | |
| SCHEMBL4074993 | 0.87 | DUT (0.34) | P2RY6P2RY14TYMPNT5EDUT | |
| SCHEMBL5878698 | 0.86 | SLC6A11 (0.39) | TYMPSLC6A1SLC6A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7569686-B1 | Compounds and methods for synthesis of bicyclic nucleic acid analogs | ISIS PHARMACEUTICALS, INC. (US) | 2009-08-04 | — | — | US | disclosed |