SCHEMBL4078779

SCHEMBL4078779

C=C(CC(C)(C)O)C(=O)O

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TET2 Q6N021 5/20 0.67
HMGCR P04035 1/20 0.42
CHRM1 P11229 1/20 0.42
TBXA2R P21731 1/20 0.42
ADRA1A P35348 1/20 0.42
TET3 O43151 1/20 0.41
TET1 Q8NFU7 1/20 0.41
ALDH1A1 P00352 3/20 0.36
TSHR P16473 2/20 0.36
PIK3CD O00329 1/20 0.35
CYP2D6 P10635 1/20 0.35
CYP2C19 P33261 1/20 0.35
HIF1A Q16665 1/20 0.35
GRIK1 P39086 1/20 0.34
GRIK2 Q13002 1/20 0.34
GRM1 Q13255 1/20 0.34
GRM2 Q14416 1/20 0.34
ALOX15 P16050 1/20 0.34
HSD17B10 Q99714 1/20 0.34
KDM4E B2RXH2 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL346723 0.86 TET2 (0.62) TET2HMGCRCHRM1TBXA2RADRA1A
SCHEMBL18497006 0.84 TET2 (0.67) TET2HMGCRCHRM1TBXA2RADRA1A
Propane SCHEMBL10621167 0.82 TET2 (0.58) TET2HMGCRCHRM1TBXA2RADRA1A
SCHEMBL22812 0.81 TET2 (0.62) TET2HMGCRCHRM1TBXA2RADRA1A
SCHEMBL4835954 0.77 TET2 (0.58) TET2HMGCRCHRM1TBXA2RADRA1A
SCHEMBL2524423 0.77 TET2 (0.64) TET2HMGCRCHRM1TBXA2RADRA1A
Hydrochloric Acid SCHEMBL28222917 0.77 TET2 (0.58) TET2HMGCRCHRM1TBXA2RADRA1A
SCHEMBL1469905 0.75 TET2 (0.56) TET2HMGCRCHRM1TBXA2RADRA1A
SCHEMBL3771386 0.75 TET2 (0.56) TET2HMGCRCHRM1TBXA2RADRA1A
Methacrylic Acid SCHEMBL6536838 0.75 TET2 (0.45) TET2HMGCRCHRM1TBXA2RADRA1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8664350-B2 Polymeric coupling agents LUBRIZOL LIMITED (GB) 2014-03-04 US claimed
EP-2084219-B1 POLYMERIC COUPLING AGENTS LUBRIZOL LTD (GB) 2012-09-05 EP claimed
US-20090306252-A1 Polymeric Coupling Agents LUBRIZOL LIMITED (GB) 2009-12-10 US claimed
EP-2084219-A1 POLYMERIC COUPLING AGENTS Lubrizol Limited (GB) 2009-08-05 EP claimed
WO-2008049840-A1 POLYMERIC COUPLING AGENTS LUBRIZOL LIMITED (GB) 2008-05-02 WO claimed
EP-0474452-B1 Thermal transfer dye image receiving sheet NEW OJI PAPER CO LTD (JP) 1995-07-12 EP claimed
CN-107922442-B Organosilicon compounds having (meth) acrylate groups and method for producing the same 瓦克化学股份公司 2020-07-03 CN disclosed
EP-3344634-B1 ORGANOSILICON COMPOUNDS HAVING (METH)ACRYLATE GROUPS AND A PROCESS FOR PREPARATION THEREOF WACKER CHEMIE AG (DE) 2019-10-02 EP disclosed
EP-3344634-A1 ORGANOSILICON COMPOUNDS HAVING (METH)ACRYLATE GROUPS AND A PROCESS FOR PREPARATION THEREOF Wacker Chemie AG (DE) 2018-07-11 EP disclosed
WO-2017036743-A1 ORGANOSILICON COMPOUNDS HAVING (METH)ACRYLATE GROUPS AND A PROCESS FOR PREPARATION THEREOF WACKER CHEMIE AG (DE) 2017-03-09 WO disclosed
US-8664350-B2 Polymeric coupling agents LUBRIZOL LIMITED (GB) 2014-03-04 US disclosed
EP-2084219-B1 POLYMERIC COUPLING AGENTS LUBRIZOL LTD (GB) 2012-09-05 EP disclosed
US-20090306252-A1 Polymeric Coupling Agents LUBRIZOL LIMITED (GB) 2009-12-10 US disclosed
EP-2084219-A1 POLYMERIC COUPLING AGENTS Lubrizol Limited (GB) 2009-08-05 EP disclosed
WO-2008049840-A1 POLYMERIC COUPLING AGENTS LUBRIZOL LIMITED (GB) 2008-05-02 WO disclosed
US-4961750-A Acrylate tanning agent ROHM GMBH (DE) 1990-10-09 US disclosed