SCHEMBL4835954

SCHEMBL4835954

C=C(CC(C)(C)N)C(=O)O

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TET2 Q6N021 5/20 0.58
TET3 O43151 1/20 0.39
TET1 Q8NFU7 1/20 0.39
GRIK1 P39086 1/20 0.38
GRIK2 Q13002 1/20 0.38
GRM1 Q13255 1/20 0.38
GRM2 Q14416 1/20 0.38
HMGCR P04035 1/20 0.35
CHRM1 P11229 1/20 0.35
TBXA2R P21731 1/20 0.35
ADRA1A P35348 1/20 0.35
KDM4E B2RXH2 1/20 0.34
CYP2D6 P10635 1/20 0.33
TSHR P16473 1/20 0.33
CYP2C19 P33261 1/20 0.33
HIF1A Q16665 1/20 0.33
ALOX15 P16050 1/20 0.33
HSD17B10 Q99714 1/20 0.33
GGT1 P19440 1/20 0.31
GRM4 Q14833 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27806694 0.80 TDP1 (0.39) TET2KDM4EGRM4TDP1
SCHEMBL22812 0.79 TET2 (0.62) TET2TET3TET1GRIK1GRIK2
SCHEMBL346723 0.79 TET2 (0.62) TET2TET3TET1GRIK1GRIK2
SCHEMBL18497006 0.77 TET2 (0.67) TET2TET3TET1GRIK1GRIK2
SCHEMBL4078779 0.77 TET2 (0.67) TET2TET3TET1GRIK1GRIK2
SCHEMBL5444612 0.76 KDM4E (0.58) TET2TET3TET1GRIK1GRIK2
SCHEMBL6472718 0.76 TET2 (0.48) TET2TET3TET1GRIK1GRIK2
Tert-Butylamine SCHEMBL7125089 0.75 TET2 (0.46) TET2TET3TET1GRIK1GRIK2
SCHEMBL2524423 0.75 TET2 (0.64) TET2TET3TET1GRIK1GRIK2
Hydrochloric Acid SCHEMBL28222917 0.75 TET2 (0.58) TET2TET3TET1GRIK1GRIK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102112191-B Graft copolymers for ion exchange chromatography MERCK PATENT GMBH 2014-07-30 CN disclosed
CN-102112191-A Graft copolymers for ion exchange chromatography MERCK PATENT GMBH 2011-06-29 CN disclosed
US-7378033-B2 Crease-resistant composition comprising a copolymer of controlled architecture, for articles made of textile fibers RHODIA CHIMIE (FR) 2008-05-27 US disclosed
US-20070094809-A1 Anti-creasing composition comprising a copolymer having a controlled architecture, for items consisting of textile fibres RHODIA CHIMIE (FR) 2007-05-03 US disclosed
US-20060127644-A1 Diffuse-reflection surfaces and process for their production CREAVIS GESELLSCHAFT FUR TECH. UND INNOVATION MBH (DE) 2006-06-15 US disclosed
CN-1204176-C Methods and Compositions AVECIA LTD (GB) 2005-06-01 CN disclosed
US-6790910-B1 ANTIMICROBIAL POLYMERS OR BLENDS MAY BE USED FOR PRODUCING HYGIENE ITEMS OR ITEMS FOR MEDICAL TECHNOLOGY, E.G. AS A COATING, OR ELSE IN SURFACE COATINGS OR PROTECTIVE PAINTS, WATER TREATMENT CREAVIS GESELLSCHAFT FUER TECHNOLOGIE UND INNOVATION MBH (DE) 2004-09-14 US disclosed
US-20040144657-A1 Process for the surface-immobililzation of anti-microbial polymers by metal deposition DEGUSSA AG (DE) 2004-07-29 US disclosed
CN-1468281-A Method and compositions 2004-01-14 CN disclosed
EP-0627476-B1 PHOTOPOLYMERIZATION INITIATOR COMPOSITION FOR VISIBLE RAY POLYMERIZABLE ADHESIVE ADELL CO LTD (JP) 1999-08-04 EP disclosed
US-5607985-A BENZOYL PHOSPHINE OXIDE, CAMPHORQUINONE ADELL CO., LTD. (JP) 1997-03-04 US disclosed
EP-0716590-A1 COSMETIC FILM FORMING COMPOSITIONS WHICH ARE FREEZE-THAW STABLE EASTMAN CHEMICAL COMPANY (US) 1996-06-19 EP disclosed
WO-1995006454-A1 COSMETIC FILM FORMING COMPOSITIONS WHICH ARE FREEZE-THAW STABLE EASTMAN CHEMICAL COMPANY (US) 1995-03-09 WO disclosed
EP-0627476-A1 PHOTOPOLYMERIZATION INITIATOR COMPOSITION FOR VISIBLE RAY POLYMERIZABLE ADHESIVE ADELL CO., LTD. (JP) 1994-12-07 EP disclosed