Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | DAPK3 | O43293 | 2/20 | 0.42 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.42 |
| ▸ | CSF1R | P07333 | 2/20 | 0.42 |
| ▸ | RET | P07949 | 2/20 | 0.42 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.42 |
| ▸ | LTK | P29376 | 2/20 | 0.42 |
| ▸ | KDR | P35968 | 2/20 | 0.42 |
| ▸ | CSNK1A1 | P48729 | 2/20 | 0.42 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.42 |
| ▸ | MAP2K1 | Q02750 | 2/20 | 0.42 |
| ▸ | PTK2 | Q05397 | 2/20 | 0.42 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.42 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.42 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.42 |
| ▸ | DYRK1B | Q9Y463 | 2/20 | 0.42 |
| ▸ | PLK4 | O00444 | 1/20 | 0.42 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.42 |
| ▸ | AURKA | O14965 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4083790 | 0.81 | CHEK1 (0.46) | TSHRMAPTDAPK3MAP4K4CSF1R | |
| SCHEMBL4072321 | 0.77 | TSHR (0.45) | TSHRMAPTLRRK2BTKALDH1A1 | |
| SCHEMBL4074966 | 0.75 | TSHR (0.44) | TSHRMAPTDAPK3MAP4K4CSF1R | |
| SCHEMBL4072131 | 0.75 | TSHR (0.44) | TSHRMAPTDAPK3MAP4K4CSF1R | |
| SCHEMBL4074971 | 0.75 | TSHR (0.44) | TSHRMAPTALDH1A1HTTKDM4E | |
| SCHEMBL4080201 | 0.75 | PTPRC (0.43) | TSHRMAPTALDH1A1KDM4EGLA | |
| SCHEMBL1534528 | 0.74 | TSHR (0.49) | TSHRMAPTDAPK3MAP4K4CSF1R | |
| SCHEMBL15687395 | 0.74 | TSHR (0.49) | TSHRMAPTDAPK3MAP4K4CSF1R | |
| SCHEMBL25242753 | 0.74 | MAPT (0.53) | MAPTDAPK3MAP4K4CSF1RRET | |
| SCHEMBL2919847 | 0.73 | MAPT (0.61) | TSHRMAPTDAPK3MAP4K4CSF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8658801-B2 | Pesticides containing a bicyclic bisamide structure | SYNGENTA CROP PROTECTION, LLC (US) | 2014-02-25 | — | — | US | disclosed |
| US-8658801-B2 | Pesticides containing a bicyclic bisamide structure | SYNGENTA CROP PROTECTION, LLC (US) | 2014-02-25 | — | — | US | disclosed |
| US-8658801-B2 | Pesticides containing a bicyclic bisamide structure | SYNGENTA CROP PROTECTION, LLC (US) | 2014-02-25 | — | — | US | disclosed |
| CN-101426779-B | Pesticide containing bicyclic bisamide structure | SYNGENTA PARTICIPATIONS AG | 2013-08-21 | — | — | CN | disclosed |
| US-20090298816-A1 | PESTICIDES CONTAINING A BICYCLIC BISAMIDE STRUCTURE | SYNGENTA CROP PROTECTION, INC. (US) | 2009-12-03 | — | — | US | disclosed |
| US-20090298816-A1 | PESTICIDES CONTAINING A BICYCLIC BISAMIDE STRUCTURE | SYNGENTA CROP PROTECTION, INC. (US) | 2009-12-03 | — | — | US | disclosed |
| US-20090298816-A1 | PESTICIDES CONTAINING A BICYCLIC BISAMIDE STRUCTURE | SYNGENTA CROP PROTECTION, INC. (US) | 2009-12-03 | — | — | US | disclosed |
| EP-1984354-B1 | PESTICIDES CONTAINING A BICYCLIC BISAMIDE STRUCTURE | SYNGENTA PARTICIPATIONS AG (CH) | 2009-08-05 | — | — | EP | disclosed |
| EP-1984354-B1 | PESTICIDES CONTAINING A BICYCLIC BISAMIDE STRUCTURE | SYNGENTA PARTICIPATIONS AG (CH) | 2009-08-05 | — | — | EP | disclosed |
| CN-101426779-A | Pesticide containing bicyclic bisamide structure | SYNGENTA PARTICIPATIONS AG (CH) | 2009-05-06 | — | — | CN | disclosed |
| EP-1984354-A1 | PESTICIDES CONTAINING A BICYCLIC BISAMIDE STRUCTURE | Syngeta Participations AG (CH) | 2008-10-29 | — | — | EP | disclosed |
| WO-2007093402-A1 | PESTICIDES CONTAINING A BICYCLIC BISAMIDE STRUCTURE | SYNGENTA PARTICIPATIONS AG (CH) | 2007-08-23 | — | — | WO | disclosed |
| WO-2007093402-A1 | PESTICIDES CONTAINING A BICYCLIC BISAMIDE STRUCTURE | SYNGENTA PARTICIPATIONS AG (CH) | 2007-08-23 | — | — | WO | disclosed |
| US-4223143-A | PYRAZOLO-QUINAZOLIN-ONES, CONTROLLING URIC ACID CONCENTRATION, GOUT, XANTHINE OXIDASE | SIEGFRIED AKTIENGESELLSCHAFT (CH) | 1980-09-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090298816-A1 | PESTICIDES CONTAINING A BICYCLIC BISAMIDE STRUCTURE | DDT, ACHE, GAP43 | TSHR 1031/4885MAPT 124/4885DAPK3 2327/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.