SCHEMBL4079174

SCHEMBL4079174

CC(=O)OCc1ccc2c(c1)Sc1ccccc1N2

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NOX1 Q9Y5S8 11/20 0.51
GAA P10253 7/20 0.51
MAPT P10636 6/20 0.51
MEN1 O00255 5/20 0.51
KMT2A Q03164 5/20 0.51
ALOX15 P16050 3/20 0.51
SNCA P37840 3/20 0.51
CYBB P04839 1/20 0.51
APP P05067 1/20 0.51
NOX3 Q9HBY0 1/20 0.51
NOX4 Q9NPH5 1/20 0.51
MAPK1 P28482 4/20 0.50
TDP1 Q9NUW8 3/20 0.50
LMNA P02545 3/20 0.50
HTT P42858 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
ALDH1A1 P00352 2/20 0.48
HSD17B10 Q99714 2/20 0.48
TSHR P16473 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8085484 0.81 NOX1 (0.60) NOX1GAAMAPTMEN1KMT2A
SCHEMBL240209 0.76 NOX1 (0.59) NOX1GAAMAPTMEN1KMT2A
SCHEMBL2609258 0.76 NOX1 (0.66) NOX1GAAMAPTMEN1KMT2A
SCHEMBL3793103 0.76 NOX1 (0.52) NOX1GAAMAPTMEN1KMT2A
SCHEMBL885118 0.76 NOX1 (0.63) NOX1GAAMAPTMEN1KMT2A
SCHEMBL6046439 0.76 SIRT2 (0.48) GAAMAPTMEN1KMT2AMAPK1
SCHEMBL2312864 0.75 NOX1 (0.57) NOX1GAAMAPTMEN1KMT2A
SCHEMBL17284846 0.75 NOX1 (0.57) NOX1GAAMAPTMEN1KMT2A
Phenothiazine SCHEMBL28750254 0.74 NOX1 (0.71) NOX1GAAMAPTMEN1KMT2A
SCHEMBL12311060 0.74 NOX1 (0.82) NOX1GAAMAPTMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7572017-B2 Signal mirror system for a vehicle DONNELLY CORPORATION (US) 2009-08-11 US disclosed
US-20050079326-A1 Electrochromic polymeric solid films, manufacturing electrochromic devices using such solid films, and processes for making such solid films and devices DONNELLY CORPORATION (US) 2005-04-14 US disclosed
US-20020041443-A1 Electrochromic mirrors and devices VARAPRASAD DESARAJU V (US) 2002-04-11 US disclosed
EP-0758929-A4 ELECTROCHROMIC MIRRORS AND DEVICES DONNELLY CORP (US) 1997-08-06 EP disclosed
EP-0758929-A1 ELECTROCHROMIC MIRRORS AND DEVICES DONNELLY CORPORATION (US) 1997-02-26 EP disclosed
WO-1995030495-A1 ELECTROCHROMIC MIRRORS AND DEVICES DONNELLY CORPORATION (US) 1995-11-16 WO disclosed