SCHEMBL885118

SCHEMBL885118

c1ccc2c(c1)Nc1ccc(Cc3ccc4c(c3)Sc3ccccc3N4)cc1S2

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NOX1 Q9Y5S8 11/20 0.63
MAPT P10636 7/20 0.63
GAA P10253 6/20 0.63
MEN1 O00255 4/20 0.63
KMT2A Q03164 4/20 0.63
SNCA P37840 4/20 0.63
TDP1 Q9NUW8 3/20 0.63
ALOX15 P16050 3/20 0.63
BCHE P06276 2/20 0.63
ACHE P22303 2/20 0.63
CYP1A2 P05177 1/20 0.63
POLB P06746 1/20 0.63
CYP3A4 P08684 1/20 0.63
ADORA3 P0DMS8 1/20 0.63
ALOX12 P18054 1/20 0.63
MAOA P21397 1/20 0.63
CNR1 P21554 1/20 0.63
PTGS1 P23219 1/20 0.63
SLC6A2 P23975 1/20 0.63
HTR2C P28335 1/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28992250 0.89 NOX1 (0.47) NOX1MAPTGAAMEN1KMT2A
SCHEMBL31512666 0.86 NOX1 (0.59) NOX1MAPTGAAMEN1KMT2A
SCHEMBL27514939 0.86 NOX1 (0.59) NOX1MAPTGAAMEN1KMT2A
SCHEMBL240209 0.86 NOX1 (0.59) NOX1MAPTGAAMEN1KMT2A
SCHEMBL2312864 0.84 NOX1 (0.57) NOX1MAPTGAAMEN1KMT2A
SCHEMBL17284846 0.84 NOX1 (0.57) NOX1MAPTGAAMEN1KMT2A
SCHEMBL25061432 0.82 NOX1 (0.53) NOX1MAPTGAAMEN1KMT2A
SCHEMBL8085484 0.82 NOX1 (0.60) NOX1MAPTGAAMEN1KMT2A
SCHEMBL31614614 0.82 NOX1 (0.53) NOX1MAPTGAAMEN1KMT2A
SCHEMBL8147738 0.82 NOX1 (0.53) NOX1MAPTGAAMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8148565-B2 Method of manufacturing an organic silicon compound that contains a methacryloxy group or an acryloxy group DOW CORNING TORAY COMPANY, LTD. (JP) 2012-04-03 US claimed
EP-1915384-B1 A METHOD OF MANUFACTURING AN ORGANIC SILICON COMPOUND THAT CONTAINS A METHACRYLOXY GROUP OR AN ACRYLOXY GROUP DOW CORNING TORAY CO LTD (JP) 2012-01-11 EP claimed
US-20090306370-A1 Method Of Manufacturing An Organic Silicon Compound That Contains A Methacryloxy Group Or An Acryloxy Group DOW TORAY CO., LTD. (JP) 2009-12-10 US claimed
EP-0332666-B1 PHENOTHIAZINE DIMERS AND OLIGOMERS, PROCESS FOR PREPARING AND USE IN REACTOR SCALE PREVENTION OCCIDENTAL CHEM CO (US) 1995-11-02 EP claimed
EP-0332666-A1 PHENOTHIAZINE DIMERS AND OLIGOMERS, PROCESS FOR PREPARING AND USE IN REACTOR SCALE PREVENTION OCCIDENTAL CHEMICAL CORPORATION (US) 1989-09-20 EP claimed
US-4855424-A ANTISCALING AGENTS FOR REACTOR WALLS DURING POLYMERIZATION OF VINYL CHLORIDE AND COMONOMER OCCIDENTAL CHEMICAL CORPORATION (US) 1989-08-08 US claimed
EP-0332666-A4 PHENOTHIAZINE DIMERS AND OLIGOMERS, PROCESS FOR PREPARING AND USE IN REACTOR SCALE PREVENTION. OCCIDENTAL CHEM CO (US) 1989-05-30 EP claimed
WO-1989000993-A1 PHENOTHIAZINE DIMERS AND OLIGOMERS, PROCESS FOR PREPARING AND USE IN REACTOR SCALE PREVENTION OCCIDENTAL CHEMICAL CORPORATION (US) 1989-02-09 WO claimed
US-8148565-B2 Method of manufacturing an organic silicon compound that contains a methacryloxy group or an acryloxy group DOW CORNING TORAY COMPANY, LTD. (JP) 2012-04-03 US disclosed
EP-1915384-B1 A METHOD OF MANUFACTURING AN ORGANIC SILICON COMPOUND THAT CONTAINS A METHACRYLOXY GROUP OR AN ACRYLOXY GROUP DOW CORNING TORAY CO LTD (JP) 2012-01-11 EP disclosed
US-20090306370-A1 Method Of Manufacturing An Organic Silicon Compound That Contains A Methacryloxy Group Or An Acryloxy Group DOW TORAY CO., LTD. (JP) 2009-12-10 US disclosed
EP-0332666-B1 PHENOTHIAZINE DIMERS AND OLIGOMERS, PROCESS FOR PREPARING AND USE IN REACTOR SCALE PREVENTION OCCIDENTAL CHEM CO (US) 1995-11-02 EP disclosed
US-4960885-A DIMERIZATION; USED AS ANTISCALING AGENTS OCCIDENTAL CHEMICAL CORPORATION (US) 1990-10-02 US disclosed
EP-0332666-A1 PHENOTHIAZINE DIMERS AND OLIGOMERS, PROCESS FOR PREPARING AND USE IN REACTOR SCALE PREVENTION OCCIDENTAL CHEMICAL CORPORATION (US) 1989-09-20 EP disclosed
US-4855424-A ANTISCALING AGENTS FOR REACTOR WALLS DURING POLYMERIZATION OF VINYL CHLORIDE AND COMONOMER OCCIDENTAL CHEMICAL CORPORATION (US) 1989-08-08 US disclosed
US-4853446-A ANTIFOULING AGENT OCCIDENTAL CHEMICAL CORPORATION (US) 1989-08-01 US disclosed
EP-0332666-A4 PHENOTHIAZINE DIMERS AND OLIGOMERS, PROCESS FOR PREPARING AND USE IN REACTOR SCALE PREVENTION. OCCIDENTAL CHEM CO (US) 1989-05-30 EP disclosed
WO-1989000993-A1 PHENOTHIAZINE DIMERS AND OLIGOMERS, PROCESS FOR PREPARING AND USE IN REACTOR SCALE PREVENTION OCCIDENTAL CHEMICAL CORPORATION (US) 1989-02-09 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090306370-A1 Method Of Manufacturing An Organic Silicon Compound That Contains A Methacryloxy Group Or An Acryloxy Group SIK1, SMS, SIK2 NOX1 3375/4885MAPT 861/4885GAA 714/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.