Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4A | O75164 | 1/20 | 0.67 |
| ▸ | KDM4B | O94953 | 1/20 | 0.67 |
| ▸ | KDM5C | P41229 | 1/20 | 0.67 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.67 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.59 |
| ▸ | KMO | O15229 | 2/20 | 0.53 |
| ▸ | RXRA | P19793 | 2/20 | 0.47 |
| ▸ | RXRB | P28702 | 2/20 | 0.47 |
| ▸ | DDT | P30046 | 1/20 | 0.47 |
| ▸ | CD74 | P04233 | 1/20 | 0.46 |
| ▸ | MIF | P14174 | 1/20 | 0.46 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.45 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.45 |
| ▸ | METAP1 | P53582 | 1/20 | 0.44 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | MAP2K4 | P45985 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31018816 | 1.00 | KDM4A (0.67) | KDM4AKDM4BKDM5CKDM5BKAT6A | |
| SCHEMBL7855714 | 0.85 | KAT6A (0.54) | KDM4AKDM4BKDM5CKDM5BKAT6A | |
| SCHEMBL1724613 | 0.81 | KAT6A (0.60) | KDM4AKDM4BKDM5CKDM5BKAT6A | |
| SCHEMBL6164638 | 0.81 | KAT6A (0.54) | KDM4AKDM4BKDM5CKDM5BKAT6A | |
| SCHEMBL600911 | 0.81 | KDM4A (0.58) | KDM4AKDM4BKDM5CKDM5BKAT6A | |
| SCHEMBL6647247 | 0.80 | KAT6A (0.53) | KDM4AKDM4BKDM5CKDM5BKAT6A | |
| SCHEMBL8193903 | 0.79 | PRSS1 (0.54) | KDM4AKDM4BKDM5CKDM5BKAT6A | |
| SCHEMBL12234338 | 0.78 | KAT6A (0.51) | KAT6ANPC1RAB9AMAPK1 | |
| SCHEMBL4536161 | 0.78 | TP53 (0.49) | KAT6ANPC1RAB9A | |
| SCHEMBL17275048 | 0.78 | KDM4A (0.51) | KDM4AKDM4BKDM5CKDM5BKAT6A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2054410-A2 | OXAZOLIDONE DERIVATIVES AS PR MODULATORS | Wyeth (US) | 2009-05-06 | — | — | EP | disclosed |
| WO-2008021331-A2 | OXAZOLIDONE DERIVATIVES AS PR MODULATORS | WYETH (US) | 2008-02-21 | — | — | WO | disclosed |