SCHEMBL4079508

SCHEMBL4079508

CC(F)N1CCC(N)CC1

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
GNAI3 P08754 1/20 0.32
GNAO1 P09471 1/20 0.32
GNAI1 P63096 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20063989 0.81 GNAI3 (0.31) GNAI3GNAO1GNAI1
SCHEMBL29044516 0.79 GNAI3 (0.30) GNAI3GNAO1GNAI1
SCHEMBL222544 0.79 CHRNA7 (0.34) GNAI3GNAO1GNAI1
SCHEMBL19020898 0.78
SCHEMBL27496417 0.77 GNAI3 (0.33) GNAI3GNAO1GNAI1
Hydrochloric Acid SCHEMBL222616 0.77 GNAI3 (0.38) GNAI3GNAO1GNAI1
Hydrochloric Acid SCHEMBL1456033 0.77 GNAI3 (0.38) GNAI3GNAO1GNAI1
SCHEMBL28999393 0.75
SCHEMBL21776120 0.75 GNAI3 (0.32) GNAI3GNAO1GNAI1
SCHEMBL28506728 0.75 GNAI3 (0.32) GNAI3GNAO1GNAI1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090170131-A1 Agents for Imaging Apoptosis BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM 2009-07-02 US claimed
US-20090170131-A1 Agents for Imaging Apoptosis BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM 2009-07-02 US disclosed
WO-2007134127-A3 AGENTS FOR IMAGING APOPTOSIS UNIV TEXAS (US) 2008-01-17 WO disclosed
WO-2007134127-A2 AGENTS FOR IMAGING APOPTOSIS BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2007-11-22 WO disclosed