Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.42 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.39 |
| ▸ | GNAO1 | P09471 | 3/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | GBA1 | P04062 | 1/20 | 0.34 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.34 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.34 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.34 |
| ▸ | GNAI3 | P08754 | 2/20 | 0.33 |
| ▸ | GNAI1 | P63096 | 2/20 | 0.33 |
| ▸ | NAMPT | P43490 | 1/20 | 0.33 |
| ▸ | RAD52 | P43351 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3668452 | 0.98 | SIGMAR1 (0.46) | SIGMAR1HRH3ITGB3ITGA2BGNAO1 | |
| SCHEMBL3389547 | 0.93 | SIGMAR1 (0.58) | SIGMAR1HRH3ITGB3ITGA2BGNAO1 | |
| SCHEMBL21799827 | 0.91 | SIGMAR1 (0.61) | SIGMAR1HRH3ITGB3ITGA2BGNAO1 | |
| SCHEMBL21799702 | 0.91 | SIGMAR1 (0.61) | SIGMAR1HRH3ITGB3ITGA2BGNAO1 | |
| SCHEMBL10597459 | 0.91 | SIGMAR1 (0.56) | SIGMAR1HRH3ITGB3ITGA2BGNAO1 | |
| SCHEMBL21800083 | 0.91 | SIGMAR1 (0.61) | SIGMAR1HRH3ITGB3ITGA2BGNAO1 | |
| SCHEMBL21799588 | 0.91 | SIGMAR1 (0.61) | SIGMAR1HRH3ITGB3ITGA2BGNAO1 | |
| SCHEMBL21799990 | 0.91 | SIGMAR1 (0.61) | SIGMAR1HRH3ITGB3ITGA2BGNAO1 | |
| SCHEMBL21800014 | 0.91 | SIGMAR1 (0.61) | SIGMAR1HRH3ITGB3ITGA2BGNAO1 | |
| SCHEMBL21799575 | 0.91 | SIGMAR1 (0.61) | SIGMAR1HRH3ITGB3ITGA2BGNAO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6846827-B1 | Pyrimidine derivatives | ASTRAZENECA AB (SE) | 2005-01-25 | — | — | US | claimed |
| EP-1226126-B1 | PYRIMIDINE DERIVATIVES | ASTRAZENECA AB (SE) | 2005-01-05 | — | — | EP | claimed |
| EP-1226126-A1 | PYRIMIDINE DERIVATIVES | AstraZeneca AB (SE) | 2002-07-31 | — | — | EP | claimed |
| WO-2001027089-A1 | PYRIMIDINE DERIVATIVES | ASTRAZENECA AB (SE) | 2001-04-19 | — | — | WO | claimed |
| EP-3623398-B1 | RESIN COMPOSITION COMPRISING A MODIFIED BLOCK COPOLYMER AND METHOD FOR PRODUCING MODIFIED BLOCK COPOLYMER | ASAHI CHEMICAL IND (JP) | 2024-08-28 | — | — | EP | disclosed |
| WO-2023104744-A1 | 3-((3-([1,1'-BIPHENYL]-3-YLMETHOXY)PHENOXY)METHYL)BENZONITRILE DERIVATIVES AND THE USE THEREOF | HELMHOLTZ-ZENTRUM DRESDEN-ROSSENDORF E.V. (DE) | 2023-06-15 | — | — | WO | disclosed |
| CN-114014845-B | Epoxy group-containing compound, liquid crystal aligning agent, and preparation method and application thereof | 波米科技有限公司 | 2023-06-02 | — | — | CN | disclosed |
| US-20230142654-A1 | NOVEL COMPOUND, PREPARATION METHOD THEREOF, AND USE THEREOF | PIMEDBIO, INC. (KR) | 2023-05-11 | — | — | US | disclosed |
| WO-2023038500-A1 | COMPOUND FOR DEGRADING ENL PROTEIN AND MEDICAL USES THEREOF | 주식회사 유빅스테라퓨틱스 | 2023-03-16 | — | — | WO | disclosed |
| CN-110603273-B | Modified block copolymer, method for producing modified block copolymer, and resin composition | 旭化成株式会社 | 2022-10-14 | — | — | CN | disclosed |
| WO-2022125862-A1 | PROCESSES FOR THE PREPARATION OF ZANUBRUTINIB AND INTERMEDIATES THEREOF | TEVA PHARMACEUTICALS INTERNATIONAL GMBH (CH) | 2022-06-16 | — | — | WO | disclosed |
| CN-114014845-A | Epoxy group-containing compound, liquid crystal aligning agent, and preparation method and application thereof | 波米科技有限公司 | 2022-02-08 | — | — | CN | disclosed |
| US-20030069299-A1 | Substituted indolinones, preparation thereof and their use as pharmaceutical compositions | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2003-04-10 | — | — | US | disclosed |
| EP-1226126-A1 | PYRIMIDINE DERIVATIVES | AstraZeneca AB (SE) | 2002-07-31 | — | — | EP | disclosed |
| WO-2001027089-A1 | PYRIMIDINE DERIVATIVES | ASTRAZENECA AB (SE) | 2001-04-19 | — | — | WO | disclosed |
| US-4871374-A | REACTION PRODUCT OF ALDEHYDE OR KETONE WITH A HETEROCYCLIC POLYAMINE | PETROLITE CORPORATION (US) | 1989-10-03 | — | — | US | disclosed |
| US-4220764-A | Preparation of tertiary heterocyclic amines | UOP INC. (US) | 1980-09-02 | — | — | US | disclosed |
| US-4179469-A | Preparation of amines | UOP INC. (US) | 1979-12-18 | — | — | US | disclosed |
| US-4079059-A | ANTIMICROBIAL, ALGAE INHIBITORS | MERCK & CO., INC. (US) | 1978-03-14 | — | — | US | disclosed |
| US-4033748-A | MICROBIOCIDES | MERCK & CO., INC. (US) | 1977-07-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230142654-A1 | NOVEL COMPOUND, PREPARATION METHOD THEREOF, AND USE THEREOF | TYR, TYRO3, TH | SIGMAR1 2723/4885HRH3 956/4885ITGB3 1814/4885 |
| US-20030069299-A1 | Substituted indolinones, preparation thereof and their use as pharmaceutical compositions | CCNI, CSNK1A1, MKI67 | SIGMAR1 1815/4885HRH3 3286/4885ITGB3 3645/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.