Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 2/20 | 0.40 |
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11923833 | 0.80 | MEN1 (0.70) | MEN1KMT2ACYP3A4ALDH1A1L3MBTL1 | |
| SCHEMBL10200133 | 0.78 | MEN1 (0.50) | MEN1KMT2ACYP3A4ALDH1A1L3MBTL1 | |
| SCHEMBL29322848 | 0.76 | KMT2A (0.51) | MEN1KMT2ACYP3A4ALDH1A1L3MBTL1 | |
| SCHEMBL12043669 | 0.76 | MEN1 (0.51) | MEN1KMT2ACYP3A4ALDH1A1L3MBTL1 | |
| SCHEMBL30179164 | 0.72 | MEN1 (0.48) | MEN1KMT2ACYP3A4ALDH1A1PDE4D | |
| SCHEMBL29324429 | 0.72 | MEN1 (0.48) | MEN1KMT2ACYP3A4ALDH1A1PDE4D | |
| SCHEMBL11164747 | 0.71 | MAOA (0.51) | MEN1KMT2ACYP3A4ALDH1A1ACHE | |
| SCHEMBL1608784 | 0.70 | HTR2C (0.50) | MEN1KMT2AMAPT | |
| SCHEMBL11923834 | 0.70 | MEN1 (1.00) | MEN1KMT2ACYP3A4ALDH1A1MAPT | |
| SCHEMBL30883376 | 0.70 | MEN1 (1.00) | MEN1KMT2ACYP3A4ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009051417-A2 | PHENANTHRENE LACTAM DERIVATIVES HAVING ANTICANCER ACTIVITY AND METHOD FOR THE PREPARATION THEREOF | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2009-04-23 | — | — | WO | disclosed |