SCHEMBL4079934

SCHEMBL4079934

Cc1ccc(C(N=C=S)N=C=S)cc1

nearest known ligand 0.42

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
MIF P14174 5/20 0.42
CHRNA7 P36544 1/20 0.38
ACHE P22303 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
TRPA1 O75762 2/20 0.35
TRPV1 Q8NER1 2/20 0.35
ALDH1A1 P00352 1/20 0.31
CYP2A6 P11509 1/20 0.31
CYP19A1 P11511 1/20 0.31
NPC1 O15118 1/20 0.30
RAB9A P51151 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11345905 0.82 MIF (0.42) MIFCHRNA7ACHETDP1TRPA1
SCHEMBL29296 0.77 CHRNA7 (0.38) CHRNA7ACHETDP1ALDH1A1CYP2A6
SCHEMBL8762415 0.77 MIF (0.42) MIFCHRNA7ACHETDP1TRPA1
SCHEMBL2001199 0.76 MIF (0.61) MIFTRPA1ALDH1A1CYP2A6
SCHEMBL11337190 0.75 MIF (0.55) MIFCHRNA7ACHECYP19A1SMN1; SMN2
SCHEMBL18422141 0.75 MIF (0.46) MIFACHETDP1ALDH1A1CYP19A1
SCHEMBL10903921 0.72 MIF (0.39) MIFACHEALDH1A1SMN1; SMN2
SCHEMBL8762285 0.69 MIF (0.78) MIFTRPA1TRPV1
SCHEMBL8764131 0.68 MIF (0.49) MIFCHRNA7ACHETDP1TRPA1
SCHEMBL332260 0.64 MIF (0.56) MIFACHETDP1ALDH1A1CYP2A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12552745-B2 Compound for optical materials, curable composition, cured body, and optical article TOKUYAMA CORPORATION (JP) 2026-02-17 US disclosed
EP-4679147-A1 MULTILAYER BODY, OPTICAL ARTICLE, COATING LAYER-CONTAINING MULTILAYER BODY, LENS, EYEGLASSES, AND FILM FOR WINDOWS TOKUYAMA CORPORATION (JP) 2026-01-14 EP disclosed
US-20250355282-A1 LAYERED BODY, OPTICAL ARTICLE, LENS, AND SPECTACLES TOKUYAMA CORPORATION (JP) 2025-11-20 US disclosed
US-20250257162-A1 CURABLE COMPOSITION, CURED BODY, LAMINATE, OPTICAL ARTICLE, LENS, AND EYEGLASSES TOKUYAMA CORPORATION (JP) 2025-08-14 US disclosed
EP-4560367-A1 LAYERED BODY, OPTICAL ARTICLE, LENS, AND SPECTACLES TOKUYAMA CORPORATION (JP) 2025-05-28 EP disclosed
EP-4516823-A1 CURABLE COMPOSITION, CURED BODY, LAMINATE, OPTICAL ARTICLE, LENS, AND SPECTACLES TOKUYAMA CORPORATION (JP) 2025-03-05 EP disclosed
CN-119072504-A Curable composition, cured product, laminate, optical article, lens, and glasses 株式会社德山 2024-12-03 CN disclosed
WO-2024080103-A1 OPTICAL MATERIAL COMPOSITION, CURED BODY, OPTICAL ARTICLE, LENS, AND SPECTACLES 株式会社トクヤマ 2024-04-18 WO disclosed
US-20240100810-A1 RESIN COMPOSITION, OPTICAL LAMINATE, OPTICAL ARTICLE, LENS AND EYEGLASSES TOKUYAMA CORPORATION (JP) 2024-03-28 US disclosed
US-11912813-B2 Urethane resin using polyrotaxane, and pad for polishing TOKUYAMA CORPORATION (JP) 2024-02-27 US disclosed
EP-2049591-A1 BIOCOMPATIBLE POLYMER COMPOSITIONS Polynovo Biomaterials Pty Limited (AU) 2009-04-22 EP disclosed
WO-2008014561-A1 BIOCOMPATIBLE POLYMER COMPOSITIONS POLYNOVO BIOMATERIALS PTY LTD (AU) 2008-02-07 WO disclosed
WO-2004011506-A1 A HIGH REFRACTIVE INDEX POLYMERIZABLE COMPOSITION PPG INDUSTRIES OHIO, INC. (US) 2004-02-05 WO disclosed
EP-1265938-A1 OPTICAL RESIN COMPOSITION PPG Industries Ohio, Inc. (US) 2002-12-18 EP disclosed
EP-1250370-A1 METHOD OF PREPARING AN OPTICAL POLYMERIZATE PPG Industries Ohio, Inc. (US) 2002-10-23 EP disclosed
EP-1250369-A1 METHOD OF PREPARING AN OPTICAL POLYMERIZATE PPG Industries Ohio, Inc. (US) 2002-10-23 EP disclosed
WO-2001036506-A1 OPTICAL RESIN COMPOSITION PPG INDUSTRIES OHIO, INC. (US) 2001-05-25 WO disclosed
WO-2001036507-A1 METHOD OF PREPARING AN OPTICAL POLYMERIZATE PPG INDUSTRIES OHIO, INC. (US) 2001-05-25 WO disclosed
WO-2001036508-A1 METHOD OF PREPARING AN OPTICAL POLYMERIZATE PPG INDUSTRIES OHIO, INC. (US) 2001-05-25 WO disclosed
US-5622826-A COUPLING WITH AN ISOCYANATE OR ISOTHIOCYANATE HOUSTON ADVANCED RESEARCH CENTER (US) 1997-04-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12552745-B2 Compound for optical materials, curable composition, cured body, and optical article C5, SCO2, ZYX MIF 2478/4885CHRNA7 2044/4885ACHE 1259/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.