Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4079927 | 0.95 | TRPV1 (0.68) | TRPV1OPRM1 | |
| SCHEMBL4077948 | 0.95 | TRPV1 (0.55) | TRPV1OPRM1 | |
| SCHEMBL4075362 | 0.89 | TRPV1 (0.59) | TRPV1OPRM1 | |
| SCHEMBL4083983 | 0.85 | TRPV1 (0.51) | TRPV1OPRM1 | |
| SCHEMBL4080172 | 0.81 | TRPV1 (0.89) | TRPV1OPRM1 | |
| SCHEMBL2527167 | 0.81 | TRPV1 (0.61) | TRPV1 | |
| SCHEMBL2531659 | 0.80 | TRPV1 (0.48) | TRPV1 | |
| SCHEMBL2532669 | 0.80 | TRPV1 (0.57) | TRPV1 | |
| SCHEMBL2531834 | 0.79 | TRPV1 (0.49) | TRPV1 | |
| SCHEMBL2527940 | 0.77 | TRPV1 (0.52) | TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2083922-A1 | VR1 RECEPTOR LIGANDS AND µ OPIOID RECEPTOR LIGANDS FOR THE TREATMENT OF PAIN | Grünenthal GmbH (DE) | 2009-08-05 | — | — | EP | claimed |
| WO-2008046647-A1 | VR1 RECEPTOR LIGANDS AND µ OPIOID RECEPTOR LIGANDS FOR THE TREATMENT OF PAIN | Grünenthal GmbH (DE) | 2008-04-24 | — | — | WO | claimed |
| EP-2083922-A1 | VR1 RECEPTOR LIGANDS AND µ OPIOID RECEPTOR LIGANDS FOR THE TREATMENT OF PAIN | Grünenthal GmbH (DE) | 2009-08-05 | — | — | EP | disclosed |
| WO-2008046647-A1 | VR1 RECEPTOR LIGANDS AND µ OPIOID RECEPTOR LIGANDS FOR THE TREATMENT OF PAIN | Grünenthal GmbH (DE) | 2008-04-24 | — | — | WO | disclosed |