Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 3/20 | 0.48 |
| ▸ | CNR2 | P34972 | 1/20 | 0.48 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | FAAH | O00519 | 9/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4184955 | 0.90 | CNR1 (0.47) | CNR1CNR2DRD3SLC6A3FAAH | |
| SCHEMBL4184959 | 0.90 | CNR1 (0.47) | CNR1CNR2DRD3SLC6A3FAAH | |
| SCHEMBL4079226 | 0.89 | CNR1 (0.47) | CNR1CNR2FAAH | |
| SCHEMBL4079568 | 0.89 | CNR1 (0.60) | CNR1CNR2FAAH | |
| SCHEMBL4075563 | 0.87 | CNR1 (0.47) | CNR1CNR2SLC6A3FAAH | |
| Selonabant SCHEMBL29482761 | 0.86 | CNR1 (0.49) | CNR1CNR2FAAH | |
| Selonabant SCHEMBL4075536 | 0.86 | CNR1 (0.49) | CNR1CNR2FAAH | |
| Selonabant SCHEMBL4075537 | 0.86 | CNR1 (0.49) | CNR1CNR2FAAH | |
| Selonabant SCHEMBL31259163 | 0.86 | CNR1 (0.49) | CNR1CNR2FAAH | |
| Selonabant SCHEMBL4075847 | 0.86 | CNR1 (0.49) | CNR1CNR2FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1620395-B1 | AZETIDINECARBOXAMIDE DERIVATIVES AND THEIR USE IN THE TREATMENT OF CB1 RECEPTOR MEDIATED DISORDERS | VERNALIS RES LTD (GB) | 2009-12-30 | — | — | EP | disclosed |
| US-7504522-B2 | Azetidinecarboxamide derivatives and their use in the treatment of cb1 receptor mediated disorders | VERNALIS RESEARCH LIMITED (GB) | 2009-03-17 | — | — | US | disclosed |
| US-20070054891-A1 | Azetidinecarboxamide derivatives and their use in the treatment of cb1 receptor mediated disorders | VERNALIS RESEARCH LIMAITED (GB) | 2007-03-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070054891-A1 | Azetidinecarboxamide derivatives and their use in the treatment of cb1 receptor mediated disorders | CNR1, CNR2, GPR119 | CNR1 1/4885CNR2 2/4885DRD3 476/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.