SCHEMBL4080308

SCHEMBL4080308

CCCCOn1nnc2ccccc21

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.59
NPSR1 Q6W5P4 1/20 0.59
RXFP1 Q9HBX9 1/20 0.59
SLC9A1 P19634 6/20 0.55
KMT2A Q03164 5/20 0.52
CYP4Z1 Q86W10 5/20 0.51
MGAM O43451 1/20 0.51
AMY1A P0DUB6 1/20 0.51
GAA P10253 1/20 0.51
SI P14410 1/20 0.51
MGAM2 Q2M2H8 1/20 0.51
NPC1 O15118 2/20 0.50
RAB9A P51151 2/20 0.50
HPGD P15428 1/20 0.50
SMN1; SMN2 Q16637 3/20 0.48
CASP3 P42574 1/20 0.48
SENP8 Q96LD8 1/20 0.48
SENP7 Q9BQF6 1/20 0.48
SENP6 Q9GZR1 1/20 0.48
MAPT P10636 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3957403 0.95 TSHR (0.58) TSHRNPSR1RXFP1SLC9A1KMT2A
SCHEMBL10433633 0.94 SLC9A1 (0.57) TSHRNPSR1RXFP1SLC9A1KMT2A
SCHEMBL9191029 0.94 SLC9A1 (0.57) TSHRNPSR1RXFP1SLC9A1KMT2A
SCHEMBL9483599 0.94 SLC9A1 (0.57) TSHRNPSR1RXFP1SLC9A1KMT2A
SCHEMBL9483441 0.90 TSHR (0.63) TSHRNPSR1RXFP1SLC9A1KMT2A
SCHEMBL17103020 0.84 TSHR (0.59) TSHRNPSR1RXFP1SLC9A1KMT2A
SCHEMBL22498386 0.84 TSHR (0.59) TSHRNPSR1RXFP1SLC9A1KMT2A
SCHEMBL4006352 0.83 TSHR (0.67) TSHRNPSR1RXFP1SLC9A1KMT2A
SCHEMBL17664885 0.82 TSHR (0.54) TSHRNPSR1RXFP1SLC9A1KMT2A
SCHEMBL17664884 0.81 TSHR (0.52) TSHRNPSR1RXFP1SLC9A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0397450-B1 NOVEL COPPER AND COPPER ALLOY CORROSION INHIBITORS CALGON CORPORATION (US) 1993-01-07 EP claimed
EP-0397450-A1 Novel copper and copper alloy corrosion inhibitors CALGON CORPORATION (US) 1990-11-14 EP claimed
WO-2024004777-A1 GREASE COMPOSITION 株式会社ADEKA 2024-01-04 WO disclosed
US-20230100774-A1 RESIN LUBRICATION GREASE COMPOSITION KYODO YUSHI CO., LTD. (JP) 2023-03-30 US disclosed
EP-4098725-A1 RESIN LUBRICATION GREASE COMPOSITION Kyodo Yushi Co., Ltd. (JP) 2022-12-07 EP disclosed
US-20210324294-A1 GREASE COMPOSITION FOR ELECTRICAL CONTACTS KYODO YUSHI CO., LTD. (JP) 2021-10-21 US disclosed
CN-101107347-B Grease composition for hub unit bearing, and hub unit bearing for vehicles NSK LTD 2011-08-17 CN disclosed
US-20090003742-A1 Grease Composition For Hub Unit Bearing, And Hub Unit Bearing For Vehicle NSK LTD. (JP) 2009-01-01 US disclosed
US-20080271967-A1 One-Way Clutch-Containing Rotation Transmission Apparatus NSK LTD. (JP) 2008-11-06 US disclosed
CN-101107347-A Grease composition for hub unit bearing, and hub unit bearing for vehicles NSK LTD (JP) 2008-01-16 CN disclosed
EP-1847586-A1 GREASE COMPOSITION FOR HUB UNIT BEARING, AND HUB UNIT BEARING FOR VEHICLES NSK Ltd., (JP) 2007-10-24 EP disclosed
EP-1770309-A1 ROTATION TRANSMISSION APPARATUS WITH BUILT-IN ONE-WAY CLUTCH NSK Ltd., (JP) 2007-04-04 EP disclosed
EP-0397450-B1 NOVEL COPPER AND COPPER ALLOY CORROSION INHIBITORS CALGON CORPORATION (US) 1993-01-07 EP disclosed
EP-0397450-A1 Novel copper and copper alloy corrosion inhibitors CALGON CORPORATION (US) 1990-11-14 EP disclosed