Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 6/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4086639 | 0.89 | AR (0.51) | AR | |
| SCHEMBL3506342 | 0.81 | AR (0.53) | AR | |
| SCHEMBL4082795 | 0.80 | AR (0.52) | AR | |
| SCHEMBL13403488 | 0.80 | AR (0.52) | AR | |
| SCHEMBL3505438 | 0.80 | AR (0.52) | AR | |
| SCHEMBL4086441 | 0.80 | AR (0.51) | AR | |
| SCHEMBL4086444 | 0.79 | AR (0.51) | AR | |
| SCHEMBL4079885 | 0.79 | AR (0.50) | AR | |
| SCHEMBL3505178 | 0.78 | AR (0.48) | AR | |
| SCHEMBL3505415 | 0.78 | AR (0.47) | AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7482357-B2 | 17-acetamido-4-azasteroid derivatives as androgen receptor modulators | MERCK & CO., INC. (US) | 2009-01-27 | — | — | US | disclosed |
| US-20060258661-A1 | 17-Acetamido-4-azasteroid derivatives as androgen receptor modulators | MERCK SHARP & DOHME CORP. | 2006-11-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060258661-A1 | 17-Acetamido-4-azasteroid derivatives as androgen receptor modulators | AR, SHBG, NR5A1 | AR 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.