Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | GMNN | O75496 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | STAT6 | P42226 | 1/20 | 0.45 |
| ▸ | PYGL | P06737 | 4/20 | 0.42 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.40 |
| ▸ | HSPA8 | P11142 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8585816 | 0.84 | HIF1A (0.42) | HIF1AKDM4EGMNNLMNAMAPT | |
| SCHEMBL6887345 | 0.84 | KDM4E (0.45) | HIF1AKDM4EGMNNLMNAMAPT | |
| SCHEMBL8752292 | 0.83 | HIF1A (0.52) | HIF1AKDM4EGMNNLMNAMAPT | |
| SCHEMBL4152180 | 0.83 | HIF1A (0.52) | HIF1AKDM4EGMNNLMNAMAPT | |
| SCHEMBL4144251 | 0.83 | HIF1A (0.52) | HIF1AKDM4EGMNNLMNAMAPT | |
| SCHEMBL9346538 | 0.74 | KDM4E (0.46) | HIF1AKDM4EGMNNLMNAMAPT | |
| SCHEMBL9346917 | 0.74 | KDM4E (0.46) | HIF1AKDM4EGMNNLMNAMAPT | |
| SCHEMBL9359905 | 0.73 | KDM4E (0.54) | HIF1AKDM4EGMNNLMNAMAPT | |
| SCHEMBL3664021 | 0.73 | KDM4E (0.54) | HIF1AKDM4EGMNNLMNAMAPT | |
| SCHEMBL11442293 | 0.72 | KDM4E (0.47) | HIF1AKDM4EGMNNLMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2084175-A1 | HCV NUCLEOSIDE INHIBITOR | Medivir AB (SE) | 2009-08-05 | — | — | EP | disclosed |
| WO-2008043704-A1 | HCV NUCLEOSIDE INHIBITOR | MEDIVIR AB (SE) | 2008-04-17 | — | — | WO | disclosed |
| US-6300490-B1 | EXPRESSION VECTOR CODING CYTOSINE DEAMINASE; FOR USE IN THE TREATMENT OF CANCERS | GLAXO WELLCOME INC. | 2001-10-09 | — | — | US | disclosed |
| US-5424295-A | Useful in treatment of varicella-zoster virus infections | BURROUGHS WELLCOME CO. (US) | 1995-06-13 | — | — | US | disclosed |