Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 13/20 | 0.53 |
| ▸ | MTNR1B | P49286 | 13/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | NSD2 | O96028 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HTR1D | P28221 | 1/20 | 0.43 |
| ▸ | HTR1B | P28222 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2205709 | 0.85 | MTNR1A (0.48) | MTNR1AMTNR1BALDH1A1 | |
| SCHEMBL2203512 | 0.85 | MTNR1A (0.48) | MTNR1AMTNR1BALDH1A1 | |
| SCHEMBL2203514 | 0.85 | MTNR1A (0.48) | MTNR1AMTNR1BALDH1A1 | |
| SCHEMBL25822216 | 0.85 | KDM4E (0.47) | MTNR1AMTNR1BKDM4ENSD2ALDH1A1 | |
| SCHEMBL13881608 | 0.85 | KDM4E (0.47) | MTNR1AMTNR1BKDM4ENSD2ALDH1A1 | |
| SCHEMBL25818089 | 0.84 | MTNR1A (0.44) | MTNR1AMTNR1BKDM4ENSD2ALDH1A1 | |
| SCHEMBL25822212 | 0.84 | MTNR1A (0.44) | MTNR1AMTNR1BKDM4ENSD2ALDH1A1 | |
| SCHEMBL4568804 | 0.82 | GPBAR1 (0.52) | MTNR1AMTNR1BHTR1DHTR1B | |
| SCHEMBL4568789 | 0.82 | GPBAR1 (0.52) | MTNR1AMTNR1BHTR1DHTR1B | |
| SCHEMBL2205571 | 0.79 | GPBAR1 (0.41) | MTNR1AMTNR1BHTR1DHTR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009045479-A1 | ALKOXY COMPOUNDS FOR DISEASE TREATMENT | ACUCELA INC. (US) | 2009-04-09 | — | — | WO | disclosed |