SCHEMBL4081340

SCHEMBL4081340

O=C(O)CCCCCOc1cccc(O)c1

nearest known ligand 0.69

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 2/20 0.67
CNR1 P21554 2/20 0.67
ALB P02768 1/20 0.57
CYSLTR2 Q9NS75 1/20 0.53
CYSLTR1 Q9Y271 1/20 0.53
PPARA Q07869 2/20 0.53
FABP1 P07148 1/20 0.52
CHRNB2 P17787 1/20 0.51
CHRNA4 P43681 1/20 0.51
HDAC1 Q13547 2/20 0.51
HDAC2 Q92769 2/20 0.51
ACSL1 P33121 1/20 0.50
ACSL6 Q9UKU0 1/20 0.50
MTNR1A P48039 1/20 0.50
MTNR1B P49286 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4086003 1.00 CNR2 (0.67) CNR2CNR1ALBCYSLTR2CYSLTR1
SCHEMBL4076679 1.00 CNR2 (0.67) CNR2CNR1ALBCYSLTR2CYSLTR1
SCHEMBL4110127 1.00 CNR2 (0.67) CNR2CNR1ALBCYSLTR2CYSLTR1
SCHEMBL4114764 1.00 CNR2 (0.67) CNR2CNR1ALBCYSLTR2CYSLTR1
SCHEMBL2158881 1.00 CNR2 (0.67) CNR2CNR1ALBCYSLTR2CYSLTR1
SCHEMBL3937528 0.98 CNR2 (0.64) CNR2CNR1ALBCYSLTR2CYSLTR1
SCHEMBL3947131 0.93 CNR2 (0.58) CNR2CNR1CYSLTR2CYSLTR1CHRNB2
Hexanoate SCHEMBL28988124 0.93 CNR2 (0.60) CNR2CNR1CYSLTR2CYSLTR1
SCHEMBL30639265 0.90 PPARA (0.58) ALBCYSLTR2CYSLTR1PPARAFABP1
Azelaic Acid SCHEMBL28605694 0.89 FFAR1 (0.63) CNR2CNR1CYSLTR2CYSLTR1HDAC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090043129-A1 POTENT AND SELECTIVE LIGANDS OF CANNABINOID RECEPTORS UNIVERSITA DEGLI STUDI DI SIENA (IT) 2009-02-12 US claimed
EP-1846364-A1 NEW POTENT AND SELECTIVE LIGANDS OF CANNABINOID RECEPTORS Universita' Degli Studi di Siena (IT) 2007-10-24 EP claimed
WO-2006080040-A1 NEW POTENT AND SELECTIVE LIGANDS OF CANNABINOID RECEPTORS UNIVERSITÀ DEGLI STUDI DI SIENA (IT) 2006-08-03 WO claimed
US-10976312-B2 Compositions and methods for capture of cellular targets of bioactive agents PROMEGA CORPORATION (US) 2021-04-13 US disclosed
US-10168323-B2 Compositions and methods for capture of cellular targets of bioactive agents PROMEGA CORPORATION (US) 2019-01-01 US disclosed
EP-2931305-B1 COMPOSITIONS AND METHODS FOR CAPTURE OF CELLULAR TARGETS OF BIOACTIVE AGENTS PROMEGA CORP (US) 2018-11-28 EP disclosed
US-20170115283-A1 COMPOSITIONS AND METHODS FOR CAPTURE OF CELLULAR TARGETS OF BIOACTIVE AGENTS JPMORGAN CHASE BANK, N.A., AS COLLATERAL AGENT 2017-04-27 US disclosed
US-9551705-B2 Compositions and methods for capture of cellular targets of bioactive agents PROMEGA CORPORATION (US) 2017-01-24 US disclosed
EP-2931305-A1 COMPOSITIONS AND METHODS FOR CAPTURE OF CELLULAR TARGETS OF BIOACTIVE AGENTS Promega Corporation (US) 2015-10-21 EP disclosed
US-20140287427-A1 COMPOSITIONS AND METHODS FOR CAPTURE OF CELLULAR TARGETS OF BIOACTIVE AGENTS PROMEGA CORPORATION (US) 2014-09-25 US disclosed
WO-2014093671-A1 COMPOSITIONS AND METHODS FOR CAPTURE OF CELLULAR TARGETS OF BIOACTIVE AGENTS PROMEGA CORPORATION (US) 2014-06-19 WO disclosed
WO-2006080040-A1 NEW POTENT AND SELECTIVE LIGANDS OF CANNABINOID RECEPTORS UNIVERSITÀ DEGLI STUDI DI SIENA (IT) 2006-08-03 WO disclosed
US-20060014921-A1 Polyhydroxyalkanoate containing amide group, sulfonic group, and sulfonate ester group, method for producing the same, and charge control agent, toner, image forming method, and image forming apparatus CANON KABUSHIKI KAISHA (JP) 2006-01-19 US disclosed
EP-1579277-A1 POLYHYDROXYALKANOATE CONTAINING AMIDE GROUP, SULFONIC GROUP, AND SULFONATE ESTER GROUP, METHOD FOR PRODUCING THE SAME, AND CHARGE CONTROL AGENT, TONER, IMAGE FORMING METHOD, AND IMAGE FORMING APPARATUS Canon Kabushiki Kaisha (JP) 2005-09-28 EP disclosed
WO-2004096188-A1 POLYHYDROXYALKANOATE-CONTAINING MAGNETIC STRUCTURE, AND MANUFACTURING METHOD AND USE THEREOF CANON KABUSHIKI KAISHA (JP) 2004-11-11 WO disclosed
WO-2004061530-A1 POLYHYDROXYALKANOATE CONTAINING AMIDE GROUP, SULFONIC GROUP, AND SULFONATE ESTER GROUP, METHOD FOR PRODUCING THE SAME, AND CHARGE CONTROL AGENT, TONER, IMAGE FORMING METHOD, AND IMAGE FORMING APPARATUS CANON KABUSHIKI KAISHA (JP) 2004-07-22 WO disclosed
US-20030180899-A1 Process for producing polyhydroxyalkanoates by utilizing microorganisms HONMA TSUTOMU (JP) 2003-09-25 US disclosed
US-6521429-B2 Using culture media and yeast extracts CANON KABUSHIKI KAISHA (JP) 2003-02-18 US disclosed
US-20010029039-A1 Polyhydroxyalkanoates and method of producing them by utilizing mircroorganisms CANON KABUSHIKI KAISHA (JP) 2001-10-11 US disclosed
EP-1118629-A2 Polyhydroxyalkanoates and method of producing them by utilizing microorganisms CANON KABUSHIKI KAISHA (JP) 2001-07-25 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090043129-A1 POTENT AND SELECTIVE LIGANDS OF CANNABINOID RECEPTORS CNR2, CNR1, GPR18 CNR2 1/4885CNR1 2/4885ALB 3315/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.