Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | PDE4A | P27815 | 1/20 | 0.56 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.56 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.56 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.56 |
| ▸ | ABL1 | P00519 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | IDO1 | P14902 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | MITF | O75030 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | JMJD6 | Q6NYC1 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7869625 | 0.85 | PDE4A (0.52) | L3MBTL1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL5868840 | 0.85 | HTT (0.69) | L3MBTL1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL5800533 | 0.83 | HTT (0.71) | L3MBTL1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL9454804 | 0.83 | SMN1; SMN2 (0.54) | LMNAALDH1A1SMN1; SMN2KDM4EALOX15 | |
| SCHEMBL7830321 | 0.83 | SMN1; SMN2 (0.56) | LMNAALDH1A1SMN1; SMN2ALOX15ALOX5 | |
| Hydrochloric Acid SCHEMBL28276875 | 0.82 | HTT (0.69) | L3MBTL1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL10851507 | 0.82 | PDE4A (0.59) | PDE4APDE4BPDE4CPDE4DABL1 | |
| SCHEMBL13985219 | 0.82 | MAPT (0.48) | L3MBTL1LMNAIDO1ALDH1A1SMN1; SMN2 | |
| SCHEMBL7280094 | 0.80 | CYP3A4 (0.67) | L3MBTL1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL3118463 | 0.79 | IDO1 (0.61) | PDE4APDE4BPDE4CPDE4DABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2083816-A2 | HETEROCYCLIC AMIDE COMPOUNDS USEFUL AS KINASE INHIBITORS | Brystol-Myers Squibb Company (US) | 2009-08-05 | — | — | EP | disclosed |
| WO-2008057775-A2 | HETEROCYCLIC AMIDE COMPOUNDS USEFUL AS KINASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2008-05-15 | — | — | WO | disclosed |
| US-5234946-A | Anticholesterol, antilipemic | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1993-08-10 | — | — | US | disclosed |
| EP-0395768-A1 | SUBSTITUTED ALLYLAMINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1990-11-07 | — | — | EP | disclosed |