Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.71 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.63 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | MAPT | P10636 | 2/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.62 |
| ▸ | MITF | O75030 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.62 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.56 |
| ▸ | ADH5 | P11766 | 2/20 | 0.56 |
| ▸ | MAOB | P27338 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | HTR2A | P28223 | 1/20 | 0.54 |
| ▸ | HTR2C | P28335 | 1/20 | 0.54 |
| ▸ | HTR2B | P41595 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28276875 | 0.99 | HTT (0.69) | HTTCYP3A4BAZ2BALDH1A1MAPT | |
| SCHEMBL4911316 | 0.91 | HTT (0.64) | HTTCYP3A4BAZ2BALDH1A1MAPT | |
| SCHEMBL6536353 | 0.85 | HTT (0.52) | HTTCYP3A4BAZ2BALDH1A1MAPT | |
| SCHEMBL9363673 | 0.84 | HTT (0.61) | HTTCYP3A4BAZ2BALDH1A1MAPT | |
| SCHEMBL5089219 | 0.83 | HTT (0.60) | HTTCYP3A4BAZ2BALDH1A1MAPT | |
| SCHEMBL4081415 | 0.83 | L3MBTL1 (0.58) | HTTALDH1A1MAPTKDM4EMEN1 | |
| SCHEMBL1022965 | 0.83 | HTT (1.00) | HTTCYP3A4BAZ2BALDH1A1MAPT | |
| SCHEMBL5733855 | 0.81 | HTT (0.61) | HTTCYP3A4ALDH1A1MEN1KMT2A | |
| SCHEMBL10669398 | 0.81 | MAPT (0.55) | HTTCYP3A4BAZ2BALDH1A1MAPT | |
| SCHEMBL2866252 | 0.81 | IKBKB (0.53) | HTTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2254871-B1 | SALTS COMPRISING ARYL-ALKYL-SUBSTITUTED IMIDAZOLIUM AND TRIAZOLIUM CATIONS AS IONIC FLUIDS | UNIV DRESDEN TECH (DE) | 2016-11-09 | — | — | EP | disclosed |
| US-9260397-B2 | Salts comprising aryl-alkyl-substituted imidazolium and triazolium cations and the use thereof | TECHNISCHE UNIVERSITAET DRESDEN (DE) | 2016-02-16 | — | — | US | disclosed |
| WO-2006058535-A2 | NOVEL N-HETEROCYCLIC PLATINUM AND PALLADIUM CARBENE COMPLEXES, PRODUCTION AND USE THEREOF FOR THE PARTIAL OXIDATION OF HYDROCARBONS | Technische Universität Dresden (DE) | 2006-06-08 | — | — | WO | disclosed |
| US-5849780-A | 1-benzenesulfonyl-1-1,3-dihydroindol-2-one derivatives, their preparation and pharmaceutical compositions in which they are present | SANOFI (FR) | 1998-12-15 | — | — | US | disclosed |
| US-5834471-A | Amide derivatives as 5HT1D receptor antagonists | SMITHKLINE BEECHAM P.L.C. (GB) | 1998-11-10 | — | — | US | disclosed |
| US-5726322-A | 1-benzenesulfonyl-1,3-dihydroindol-2-one derivatives, their preparation and pharmaceutical compositions in which they are present | SANOFI (FR) | 1998-03-10 | — | — | US | disclosed |
| US-5686624-A | 1-benzenesulfonyl-1,3-dihydro-indol-2-one derivatives, their preparation and pharmaceutical compositions in which they are present | SANOFI (FR) | 1997-11-11 | — | — | US | disclosed |
| US-5663431-A | CHEMICAL INTERMEDIATES | SANOFI (FR) | 1997-09-02 | — | — | US | disclosed |
| EP-0712397-A1 | AMIDE DERIVATIVES AS 5HT1D RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1996-05-22 | — | — | EP | disclosed |
| EP-0496237-B1 | N-imidazolyl derivatives of substituted tetrahydrocarbazole and cyclohept[b]indole | PHARMACIA SPA (IT) | 1996-02-14 | — | — | EP | disclosed |
| US-5294621-A | Thieno tetrahydropyridines useful as class III antiarrhythmic agents | ORTHO PHARMACEUTICAL CORPORATION (US) | 1994-03-15 | — | — | US | disclosed |
| US-5246957-A | Thromboxane A2 synthesis for cardiovascular disorders | FARMITALIA CARLO ERBA S.R.L. (IT) | 1993-09-21 | — | — | US | disclosed |
| US-5238953-A | Thromboxane a2 antagonist | FARMITALIA CARLO ERBA S.R.L. (IT) | 1993-08-24 | — | — | US | disclosed |
| EP-0510398-A2 | N-Imidazolyl derivatives of substituted indole | PHARMACIA S.p.A. (IT) | 1992-10-28 | — | — | EP | disclosed |
| US-5137896-A | Useful in treatment of gastrointestinal and psychic disorder; analgesic, antiemetic and antiulcer agent | JANSSEN PHARMACEUTICA N.V. (BE) | 1992-08-11 | — | — | US | disclosed |
| EP-0496237-A2 | N-imidazolyl derivatives of substituted tetrahydrocarbazole and cyclohept[b]indole | PHARMACIA S.p.A. (IT) | 1992-07-29 | — | — | EP | disclosed |
| US-5057525-A | Stimulators of gastrointestinal motility | JANSSEN PHARMACEUTICA N.V. (BE) | 1991-10-15 | — | — | US | disclosed |
| US-4962115-A | Stimulate motility of gastrointestinal system | JANSSEN PHARMACEUTICA N.V. (BE) | 1990-10-09 | — | — | US | disclosed |
| EP-0076530-B1 | NOVEL N-(3-HYDROXY-4-PIPERIDINYL)BENZAMIDE DERIVATIVES | JANSSEN PHARMACEUTICA N.V. (BE) | 1985-12-11 | — | — | EP | disclosed |
| EP-0076530-A2 | Novel N-(3-hydroxy-4-piperidinyl)benzamide derivatives | JANSSEN PHARMACEUTICA N.V. (BE) | 1983-04-13 | — | — | EP | disclosed |