Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 6/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | KDR | P35968 | 1/20 | 0.44 |
| ▸ | KYAT1 | Q16773 | 2/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4081557 | 1.00 | GAA (0.52) | GAALMNAALDH1A1NPSR1HPGD | |
| SCHEMBL16681749 | 0.85 | ABCB1 (0.46) | GAALMNAALDH1A1NPSR1HPGD | |
| SCHEMBL16681747 | 0.85 | ABCB1 (0.46) | GAALMNAALDH1A1NPSR1HPGD | |
| SCHEMBL23348046 | 0.83 | GAA (0.58) | GAALMNAALDH1A1NPSR1HPGD | |
| SCHEMBL4551177 | 0.82 | MAPT (0.48) | GAALMNAALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL4551178 | 0.82 | MAPT (0.48) | GAALMNAALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL24584758 | 0.81 | CES2 (0.49) | GAALMNAALDH1A1NPSR1SMN1; SMN2 | |
| SCHEMBL3716151 | 0.80 | CES2 (0.47) | GAALMNAALDH1A1NPSR1HPGD | |
| SCHEMBL3716153 | 0.80 | CES2 (0.47) | GAALMNAALDH1A1NPSR1HPGD | |
| SCHEMBL6786789 | 0.80 | GAA (0.60) | GAALMNAALDH1A1NPSR1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009053799-A1 | NOVEL CANNABINOID RECEPTOR LIGANDS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND PROCESS FOR THEIR PREPARATION | GLENMARK PHARMACEUTICALS, S.A. (US) | 2009-04-30 | — | — | WO | disclosed |