Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SNCA | P37840 | 5/20 | 0.59 |
| ▸ | MDM4 | O15151 | 1/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.58 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 3/20 | 0.56 |
| ▸ | RAB9A | P51151 | 3/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30758797 | 1.00 | SNCA (0.59) | SNCAMDM4TP53HDAC3MAPK1 | |
| SCHEMBL14289944 | 0.88 | MEN1 (0.50) | SNCAMDM4TP53HDAC3MAPK1 | |
| SCHEMBL8277234 | 0.85 | NPC1 (0.56) | SNCAMDM4TP53HDAC3MAPK1 | |
| SCHEMBL7707926 | 0.84 | MEN1 (0.53) | MAPK1POLBNPC1RAB9ACYP1A2 | |
| SCHEMBL27664630 | 0.84 | SNCA (0.57) | SNCAMDM4TP53HDAC3MAPK1 | |
| SCHEMBL29954708 | 0.83 | SNCA (0.61) | SNCAMDM4TP53HDAC3MAPK1 | |
| SCHEMBL11319558 | 0.82 | F10 (0.74) | SNCATP53HDAC3HDAC1HDAC2 | |
| SCHEMBL13838766 | 0.82 | NPC1 (0.55) | HDAC3HDAC1HDAC2HPGDNPC1 | |
| SCHEMBL13888851 | 0.82 | SMN1; SMN2 (0.58) | SNCAHDAC3MAPK1HDAC1HDAC2 | |
| SCHEMBL6694722 | 0.82 | LMNA (0.48) | SNCAPOLBHPGDNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117550997-A | LAT1 inhibitor and preparation method and application thereof | 中国药科大学 | 2024-02-13 | — | — | CN | disclosed |
| CN-117466761-A | Glutamine transport inhibitor, pharmaceutical composition and application | 中国药科大学 | 2024-01-30 | — | — | CN | disclosed |
| CN-110218137-B | Synthetic method of anthranilic aldehyde compound | 上海交通大学 | 2021-01-22 | — | — | CN | disclosed |
| JP-2009107972-A | AMINOBENZALDEHYDE COMPOUND, METHOD FOR PRODUCING THE SAME, AND METHOD FOR PRODUCING AMINOBENZOIC ACID COMPOUND | FUJI CHEM IND CO LTD | 2009-05-21 | — | — | JP | disclosed |
| JP-2009106923-A | CATALYTIC HYDROGENATION METHOD AND NOVEL CATALYST THEREFORE | EMMELLEN BIOTECH PHARMACEUTICALS LTD | 2009-05-21 | — | — | JP | disclosed |
| EP-1845083-A2 | New arylsulfonohydrazide inhibitors of enzymes MurC and MurD | UNIVERZA V LJUBLJANI, FAKULTETA ZA FARMACIJO (SI) | 2007-10-17 | — | — | EP | disclosed |
| US-20060058366-A1 | Jnk inhibitor | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2006-03-16 | — | — | US | disclosed |
| EP-1582211-A1 | JNK INHIBITOR | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2005-10-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060058366-A1 | Jnk inhibitor | MAPK3, MAPK4, MAPKAPK3 | SNCA 4594/4885MDM4 2033/4885TP53 2856/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.