SCHEMBL40822

SCHEMBL40822

NC(=O)Cc1c[nH]c2ccccc12

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.68
ALDH1A1 P00352 5/20 0.68
MEN1 O00255 4/20 0.68
KMT2A Q03164 4/20 0.68
SMN1; SMN2 Q16637 2/20 0.68
KDM4E B2RXH2 2/20 0.68
HPGD P15428 1/20 0.68
LMNA P02545 2/20 0.64
GAA P10253 2/20 0.64
SLC6A2 P23975 1/20 0.64
FNTA P49354 1/20 0.64
FNTB P49356 1/20 0.64
NPSR1 Q6W5P4 1/20 0.64
PKM P14618 1/20 0.60
CYP3A4 P08684 2/20 0.58
AHR P35869 1/20 0.58
GPR84 Q9NQS5 1/20 0.58
TDP1 Q9NUW8 1/20 0.58
MPO P05164 2/20 0.58
TSHR P16473 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3262116 1.00 MAPT (0.68) MAPTALDH1A1MEN1KMT2ASMN1; SMN2
SCHEMBL29376364 1.00 MAPT (0.68) MAPTALDH1A1MEN1KMT2ASMN1; SMN2
Hydrochloric Acid SCHEMBL4598405 0.98 MAPT (0.66) MAPTALDH1A1MEN1KMT2ASMN1; SMN2
Hydrochloric Acid SCHEMBL30295582 0.98 MAPT (0.66) MAPTALDH1A1MEN1KMT2ASMN1; SMN2
Acetic Acid SCHEMBL27760596 0.94 MEN1 (0.65) MAPTALDH1A1MEN1KMT2ASMN1; SMN2
Tryptamine SCHEMBL28351329 0.91 CYP1A2 (0.73) MAPTALDH1A1MEN1KMT2ASMN1; SMN2
Trifluoroacetic Acid SCHEMBL5656023 0.89 MAPT (0.60) MAPTALDH1A1MEN1KMT2ASMN1; SMN2
SCHEMBL5717728 0.86 MAPT (0.73) MAPTALDH1A1MEN1KMT2ASMN1; SMN2
Indole-3-Acetic Acid SCHEMBL2269865 0.86 MAPT (0.69) MAPTALDH1A1MEN1KMT2ASMN1; SMN2
SCHEMBL24577957 0.86 MAPT (0.68) MAPTALDH1A1MEN1KMT2ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2013 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4747627-A1 METHODS AND SYSTEMS FOR PREDICTIVE CLASSIFICATION BY MASS SPECTROMETRY AND TRAINED LARGE SPECTRAL MODELS Matterworks Inc (US) 2026-05-27 EP claimed
CN-122031539-A Pine bark polyphenol extract and preparation method and application thereof 北京农学院 2026-05-15 CN claimed
EP-4739326-A2 PRODUCTION & SECRETION OF AUXIN-LIKE MOLECULES IN BACTERIA SNIPR Biome ApS (DK) 2026-05-13 EP claimed
EP-3869192-B1 METHOD FOR QUANTITATIVE DETECTION OF VARIOUS METABOLITES IN BIOLOGICAL SAMPLE HUMAN METABOLOMICS INST INC (CN) 2026-05-13 EP claimed
EP-4633626-A1 COSMETIC USE OF A COMPOSITION FOR CARING FOR KERATIN MATERIALS COMPRISING AT LEAST INDOLE-3-ACETAMIDE L'OREAL (FR) 2025-10-22 EP claimed
US-20250258146-A1 QUANTITATIVE DETECTION METHOD OF MULTIPLE METABOLITES IN BIOLOGICAL SAMPLE AND METABOLIC CHIP HUMAN METABOLOMICS INSTITUTE INC. (CN) 2025-08-14 US claimed
US-20250246314-A1 METHODS FOR THE DETECTION AND TREATMENT OF PANCREATIC DUCTAL ADENOCARCINOMA BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM 2025-07-31 US claimed
CN-120195409-A Composition for diagnosing sepsis and medicament for sepsis preventive treatment 北京大学第三医院(北京大学第三临床医学院) 2025-06-24 CN claimed
CN-119955689-A Lactobacillus reuteri BYN and application thereof in preparation of anti-claustrade beverage 自然资源部第一海洋研究所 2025-05-09 CN claimed
CN-119874598-A Indole-3-acetamide derivative and preparation method and application thereof 河北农业大学 2025-04-25 CN claimed
US-5426041-A Binary cryptocytotoxic method of hybrid seed production PIONEER HI-BRED INTERNATIONAL, INC. (US) 1995-06-20 US claimed
CN-1098715-A PLA 2 inhibitors 1H-indole-3-acetamide compounds LILLY CO ELI (US) 1995-02-15 CN claimed
EP-0636310-A1 Doubled haploids SANDOZ LTD. (CH) 1995-02-01 EP claimed
EP-0620215-A1 1H-indole-3-acetamide derivatives as sPLA2 inhibitors ELI LILLY AND COMPANY (US) 1994-10-19 EP claimed
WO-1994015956-A1 ENDOTHELIN CONVERTING ENZYME INHIBITORS THE WELLCOME FOUNDATION LIMITED (GB) 1994-07-21 WO claimed
EP-0540561-A1 BINARY CRYPTOCYTOTOXIC METHOD OF HYBRID SEED PRODUCTION PALADIN HYBRIDS INC (CA) 1993-05-12 EP claimed
WO-1992001799-A1 BINARY CRYPTOCYTOTOXIC METHOD OF HYBRID SEED PRODUCTION PALADIN HYBRIDS INC. (CA) 1992-02-06 WO claimed
EP-0454651-A2 Novel platelet-aggregation inhibitors MONSANTO COMPANY (US) 1991-10-30 EP claimed
US-5037808-A Indolyl platelet-aggregation inhibitors MONSANTO CO. (US) 1991-08-06 US claimed
US-4411684-A Auxin compositions of N-phenyl and N-chloro phenyl indolyl-3-alkylene amides and their use as auxin growth regulators THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) 1983-10-25 US claimed