Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.69 |
| ▸ | MEN1 | O00255 | 7/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.69 |
| ▸ | HPGD | P15428 | 2/20 | 0.69 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.65 |
| ▸ | FNTA | P49354 | 1/20 | 0.65 |
| ▸ | FNTB | P49356 | 1/20 | 0.65 |
| ▸ | LMNA | P02545 | 3/20 | 0.60 |
| ▸ | TSHR | P16473 | 3/20 | 0.59 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.59 |
| ▸ | MPO | P05164 | 2/20 | 0.59 |
| ▸ | BLM | P54132 | 1/20 | 0.59 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 2/20 | 0.58 |
| ▸ | RECQL | P46063 | 2/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Indole-3-Acetic Acid SCHEMBL26344 | 0.95 | MEN1 (0.75) | MAPTMEN1KMT2AALDH1A1KDM4E | |
| Indole-3-Acetic Acid SCHEMBL29350750 | 0.95 | MEN1 (0.75) | MAPTMEN1KMT2AALDH1A1KDM4E | |
| Indole-3-Acetic Acid SCHEMBL7887240 | 0.95 | MEN1 (0.75) | MAPTMEN1KMT2AALDH1A1KDM4E | |
| Indole-3-Acetic Acid SCHEMBL31152574 | 0.93 | MEN1 (0.73) | MAPTMEN1KMT2AALDH1A1KDM4E | |
| Indole-3-Acetic Acid SCHEMBL1375190 | 0.93 | MEN1 (0.73) | MAPTMEN1KMT2AALDH1A1KDM4E | |
| Indole-3-Acetic Acid SCHEMBL31084632 | 0.93 | MEN1 (0.73) | MAPTMEN1KMT2AALDH1A1KDM4E | |
| Indole-3-Acetic Acid SCHEMBL11125791 | 0.93 | MEN1 (0.73) | MAPTMEN1KMT2AALDH1A1KDM4E | |
| Indole-3-Acetic Acid SCHEMBL468233 | 0.93 | MEN1 (0.73) | MAPTMEN1KMT2AALDH1A1KDM4E | |
| Indole-3-Acetic Acid SCHEMBL29272533 | 0.93 | MEN1 (0.73) | MAPTMEN1KMT2AALDH1A1KDM4E | |
| Indole-3-Acetic Acid SCHEMBL29272696 | 0.93 | MEN1 (0.73) | MAPTMEN1KMT2AALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110190267-A1 | PRODRUGS OF OPIOIDS AND USES THEREOF | SHIRE PHARMACEUTICALS, INC. (US) | 2011-08-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110190267-A1 | PRODRUGS OF OPIOIDS AND USES THEREOF | OPRK1, OPRL1, OPRM1 | MAPT 2248/4885MEN1 4826/4885KMT2A 1851/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.