Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 2/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.44 |
| ▸ | HTR2A | P28223 | 2/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
| ▸ | EED | O75530 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22320209 | 0.82 | SLC6A2 (0.41) | SLC6A2SLC6A4HTR2A | |
| SCHEMBL13180801 | 0.78 | SLC6A2 (0.43) | SLC6A2SLC6A4HTR2AHTR2CEED | |
| SCHEMBL14685790 | 0.77 | SLC6A2 (0.46) | SLC6A2SLC6A4HTR2AHTR2CEED | |
| SCHEMBL21725644 | 0.77 | SLC6A2 (0.44) | SLC6A2SLC6A4HTR2AHTR2CEED | |
| SCHEMBL15472525 | 0.74 | HTR2A (0.37) | HTR2AHTR2CEED | |
| SCHEMBL19564699 | 0.74 | HTR2A (0.41) | HTR2AHTR2C | |
| SCHEMBL2178459 | 0.74 | CDK4 (0.43) | SLC6A2SLC6A4 | |
| SCHEMBL15723623 | 0.73 | HTR2A (0.68) | HTR2AHTR2C | |
| SCHEMBL24143785 | 0.73 | HTR2A (0.46) | SLC6A2SLC6A4HTR2AHTR2CGRM2 | |
| SCHEMBL21725615 | 0.73 | ESR1 (0.39) | SLC6A2SLC6A4HTR2AHTR2CEED |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009055674-A1 | PYRROLOPYRIMIDINE ALKYNYL COMPOUNDS AND METHODS OF MAKING AND USING SAME | TARGEGEN INC. (US) | 2009-04-30 | — | — | WO | disclosed |
| WO-2009055674-A1 | PYRROLOPYRIMIDINE ALKYNYL COMPOUNDS AND METHODS OF MAKING AND USING SAME | TARGEGEN INC. (US) | 2009-04-30 | — | — | WO | disclosed |