SCHEMBL22320209

SCHEMBL22320209

C[CH]C(C)n1ccc2cccc(Br)c21

nearest known ligand 0.41

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 1/20 0.41
SLC6A4 P31645 1/20 0.41
HTR2A P28223 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4082423 0.82 SLC6A2 (0.44) SLC6A2SLC6A4HTR2A
SCHEMBL22320207 0.71
SCHEMBL2178459 0.69 CDK4 (0.43) SLC6A2SLC6A4
SCHEMBL24143785 0.68 HTR2A (0.46) SLC6A2SLC6A4HTR2A
SCHEMBL20876116 0.68
SCHEMBL22320201 0.67 HTR2A (0.37) HTR2A
SCHEMBL22320217 0.67 HTR2A (0.33) SLC6A2SLC6A4HTR2A
SCHEMBL22320203 0.67 HTR2A (0.49) SLC6A2SLC6A4HTR2A
SCHEMBL6505950 0.65 SLC6A2 (0.35) SLC6A2SLC6A4
SCHEMBL22955613 0.65 SLC6A2 (0.33) SLC6A2SLC6A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220167615-A1 FUNGICIDAL COMPOSITIONS SYNGENTA CROP PROTECTION AG (CH) 2022-06-02 US claimed
EP-3952652-A1 FUNGICIDAL COMPOSITIONS Syngenta Crop Protection AG (CH) 2022-02-16 EP claimed
WO-2020208096-A1 FUNGICIDAL COMPOSITIONS SYNGENTA CROP PROTECTION AG (CH) 2020-10-15 WO claimed
WO-2024068520-A1 3-(HETERO)ARYL-5-CHLORODIFLUOROMETHYL-1,2,4-OXADIAZOLE AS FUNGICIDE BAYER AKTIENGESELLSCHAFT (DE) 2024-04-04 WO disclosed
WO-2024068517-A1 3-(HETERO)ARYL-5-CHLORODIFLUOROMETHYL-1,2,4-OXADIAZOLE AS FUNGICIDE BAYER AKTIENGESELLSCHAFT (DE) 2024-04-04 WO disclosed
WO-2024068518-A1 3-HETEROARYL-5-CHLORODIFLUOROMETHYL-1,2,4-OXADIAZOLE AS FUNGICIDE BAYER AKTIENGESELLSCHAFT (DE) 2024-04-04 WO disclosed
WO-2024068519-A1 3-(HETERO)ARYL-5-CHLORODIFLUOROMETHYL-1,2,4-OXADIAZOLE AS FUNGICIDE BAYER AKTIENGESELLSCHAFT (DE) 2024-04-04 WO disclosed
WO-2024018016-A1 CRYSTALLINE FORMS OF 1,2,4-OXADIAZOLE FUNGICIDES SYNGENTA CROP PROTECTION AG (CH) 2024-01-25 WO disclosed
US-20240023551-A1 USE OF DHODH INHIBITOR FOR CONTROLLING RESISTANT PHYTOPATHOGENIC FUNGI IN CROPS BAYER AKTIENGESELLSCHAFT (DE) 2024-01-25 US disclosed
EP-4295688-A1 ACTIVE COMPOUND COMBINATION Bayer Aktiengesellschaft (DE) 2023-12-27 EP disclosed
WO-2023213670-A1 CRYSTALLINE FORMS OF (5S)-3-[3-(3-CHLORO-2-FLUOROPHENOXY)-6-METHYLPYRIDAZIN-4-YL]-5-(2-CHLORO-4-METHYLBENZYL)-5,6-DIHYDRO-4H-1,2,4-OXADIAZINE BAYER AKTIENGESELLSCHAFT (DE) 2023-11-09 WO disclosed
WO-2023213626-A1 USE OF (5S)-3-[3-(3-CHLORO-2-FLUOROPHENOXY)-6-METHYLPYRIDAZIN-4-YL]-5-(2-CHLORO-4-METHYLBENZYL)-5,6-DIHYDRO-4H-1,2,4-OXADIAZINE FOR CONTROLLING UNWANTED MICROORGANISMS BAYER AKTIENGESELLSCHAFT (DE) 2023-11-09 WO disclosed
US-11629138-B2 Microbiocidal picolinamide derivatives SYNGENTA PARTICIPATIONS AG (CH) 2023-04-18 US disclosed
EP-3692029-B1 MICROBIOCIDAL PICOLINAMIDE DERIVATIVES SYNGENTA PARTICIPATIONS AG (CH) 2023-04-12 EP disclosed
US-20220167615-A1 FUNGICIDAL COMPOSITIONS SYNGENTA CROP PROTECTION AG (CH) 2022-06-02 US disclosed
EP-3952652-A1 FUNGICIDAL COMPOSITIONS Syngenta Crop Protection AG (CH) 2022-02-16 EP disclosed
WO-2020208096-A1 FUNGICIDAL COMPOSITIONS SYNGENTA CROP PROTECTION AG (CH) 2020-10-15 WO disclosed
US-20200255400-A1 Microbiocidal Picolinamide Derivatives SYNGENTA PARTICIPATIONS AG (CH) 2020-08-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200255400-A1 Microbiocidal Picolinamide Derivatives PRF1, CASP1, FPR1 SLC6A2 3920/4885SLC6A4 3476/4885HTR2A 1946/4885
US-20240023551-A1 USE OF DHODH INHIBITOR FOR CONTROLLING RESISTANT PHYTOPATHOGENIC FUNGI IN CROPS DHODH, SDHA, SDHB SLC6A2 3082/4885SLC6A4 2938/4885HTR2A 3634/4885
US-11629138-B2 Microbiocidal picolinamide derivatives PRF1, CASP1, FPR1 SLC6A2 3920/4885SLC6A4 3476/4885HTR2A 1946/4885
US-20220167615-A1 FUNGICIDAL COMPOSITIONS CYP51A1, CYP4X1, CYP1B1 SLC6A2 4535/4885SLC6A4 4314/4885HTR2A 3983/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.