Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.68 |
| ▸ | MEN1 | O00255 | 6/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.68 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.68 |
| ▸ | RAB9A | P51151 | 8/20 | 0.62 |
| ▸ | NPC1 | O15118 | 5/20 | 0.62 |
| ▸ | LMNA | P02545 | 5/20 | 0.62 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.52 |
| ▸ | TYR | P14679 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | LTA4H | P09960 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24590457 | 0.85 | MAOB (0.57) | MAPTMEN1KMT2AALDH1A1NPSR1 | |
| SCHEMBL24590360 | 0.84 | NPY5R (0.57) | MAPTMEN1KMT2AALDH1A1NPSR1 | |
| SCHEMBL24590352 | 0.84 | TYR (0.67) | MAPTMEN1KMT2AALDH1A1NPSR1 | |
| SCHEMBL4075012 | 0.84 | MAPT (0.59) | MAPTMEN1KMT2AALDH1A1NPSR1 | |
| SCHEMBL3170512 | 0.84 | MAPT (0.59) | MAPTMEN1KMT2AALDH1A1NPSR1 | |
| SCHEMBL4077819 | 0.84 | MAPT (0.59) | MAPTMEN1KMT2AALDH1A1NPSR1 | |
| SCHEMBL1745407 | 0.83 | MEN1 (0.60) | MAPTMEN1KMT2AALDH1A1RAB9A | |
| SCHEMBL8171460 | 0.81 | MAPT (0.74) | MAPTMEN1KMT2AALDH1A1NPSR1 | |
| SCHEMBL24590324 | 0.81 | PTGS2 (0.67) | MAPTMEN1KMT2AALDH1A1RAB9A | |
| SCHEMBL4078208 | 0.81 | MAPT (0.59) | MAPTMEN1KMT2AALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2054410-A2 | OXAZOLIDONE DERIVATIVES AS PR MODULATORS | Wyeth (US) | 2009-05-06 | — | — | EP | disclosed |
| WO-2008021331-A2 | OXAZOLIDONE DERIVATIVES AS PR MODULATORS | WYETH (US) | 2008-02-21 | — | — | WO | disclosed |