SCHEMBL4082570

SCHEMBL4082570

O=C1O[C@H](CNSc2ccoc2)CN1c1ccc(N2CCSCC2)c(F)c1

nearest known ligand 0.64

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
MAOB P27338 10/20 0.64
MAOA P21397 4/20 0.64
F10 P00742 10/20 0.58
LMNA P02545 1/20 0.51
PTGS1 P23219 1/20 0.51
CALML3 P27482 1/20 0.51
SDHA P31040 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4093270 0.90 MAOB (0.63) MAOBMAOAF10LMNAPTGS1
SCHEMBL4082340 0.88 MAOB (0.49) MAOBMAOAF10LMNAPTGS1
SCHEMBL4099425 0.85 MAOB (0.67) MAOBMAOAF10LMNAPTGS1
SCHEMBL4082568 0.84 MAOB (0.64) MAOBMAOAF10LMNAPTGS1
SCHEMBL4099417 0.82 MAOB (0.73) MAOBMAOAF10LMNAPTGS1
SCHEMBL4082562 0.81 MAOB (0.69) MAOBMAOAF10LMNAPTGS1
SCHEMBL5216684 0.79 MAOB (0.84) MAOBMAOAF10LMNAPTGS1
SCHEMBL6040542 0.78 MAOB (0.85) MAOBMAOAF10LMNAPTGS1
SCHEMBL18410592 0.78 MAOB (0.80) MAOBMAOAF10LMNAPTGS1
SCHEMBL7846260 0.78 MAOB (0.79) MAOBMAOAF10LMNAPTGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090005369-A1 Oxazolidinone Compounds and Compositions and Methods Related Thereto FERRER INTERNACIONAL S.A. (ES) 2009-01-01 US disclosed
EP-1786805-A1 OXAZOLIDINONE COMPOUNDS AND COMPOSITIONS AND METHODS RELATED THERETO FERRER INTERNACIONAL, S.A. (ES) 2007-05-23 EP disclosed
WO-2006010756-A1 OXAZOLIDINONE COMPOUNDS AND COMPOSITIONS AND METHODS RELATED THERETO FERRER INTERNACIONAL, S. A. (ES) 2006-02-02 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090005369-A1 Oxazolidinone Compounds and Compositions and Methods Related Thereto OXA1L, MAOA, NR0B1 MAOB 8/4885MAOA 2/4885F10 1663/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.