Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.53 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 2/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.40 |
| ▸ | TYR | P14679 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 2/20 | 0.39 |
| ▸ | MIF | P14174 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1253728 | 0.85 | SLC7A5 (0.65) | SLC7A5TAAR1SLC6A2ESR1ESR2 | |
| SCHEMBL11456 | 0.85 | SLC7A5 (0.65) | SLC7A5TAAR1SLC6A2ESR1ESR2 | |
| Tyrosine SCHEMBL28311842 | 0.78 | SLC7A5 (0.86) | SLC7A5 | |
| Tyrosine SCHEMBL28207953 | 0.78 | SLC7A5 (0.86) | SLC7A5TAAR1SLC6A2 | |
| Tyrosine SCHEMBL28148516 | 0.78 | SLC7A5 (0.86) | SLC7A5 | |
| SCHEMBL4453960 | 0.77 | SLC7A5 (0.67) | SLC7A5TAAR1SLC6A2ESR1ESR2 | |
| SCHEMBL27680265 | 0.77 | SLC7A5 (0.67) | SLC7A5TAAR1SLC6A2ESR1ESR2 | |
| SCHEMBL28207952 | 0.77 | SLC7A5 (0.57) | SLC7A5TAAR1SLC6A2ESR1ESR2 | |
| SCHEMBL321221 | 0.76 | SLC7A5 (0.61) | SLC7A5TAAR1SLC6A2ESR1ESR2 | |
| SCHEMBL27967418 | 0.76 | SLC7A5 (0.66) | SLC7A5TAAR1SLC6A2ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7572607-B2 | Polypeptides and biosynthetic pathways for the production of monatin and its precursors | CARGILL, INCORPORATED (US) | 2009-08-11 | — | — | US | claimed |