SCHEMBL11456

SCHEMBL11456

NOC(=O)[C@@H](N)Cc1ccc(O)cc1

nearest known ligand 0.65

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 2/20 0.65
TAAR1 Q96RJ0 3/20 0.50
SLC6A2 P23975 1/20 0.50
HDAC8 Q9BY41 2/20 0.49
DPP4 P27487 1/20 0.48
ESR1 P03372 2/20 0.47
ESR2 Q92731 2/20 0.47
IDO1 P14902 2/20 0.45
TYR P14679 1/20 0.45
ALPI P09923 1/20 0.44
PKM P14618 1/20 0.44
PTGS1 P23219 1/20 0.44
XIAP P98170 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1253728 1.00 SLC7A5 (0.65) SLC7A5TAAR1SLC6A2HDAC8DPP4
SCHEMBL4453960 0.91 SLC7A5 (0.67) SLC7A5TAAR1SLC6A2HDAC8DPP4
SCHEMBL27680265 0.91 SLC7A5 (0.67) SLC7A5TAAR1SLC6A2HDAC8DPP4
SCHEMBL28698329 0.87 SLC7A5 (0.62) SLC7A5TAAR1SLC6A2HDAC8DPP4
SCHEMBL28698332 0.87 SLC7A5 (0.62) SLC7A5TAAR1SLC6A2HDAC8DPP4
SCHEMBL27967418 0.86 SLC7A5 (0.66) SLC7A5TAAR1SLC6A2HDAC8ESR1
SCHEMBL4279625 0.86 SLC7A5 (0.61) SLC7A5TAAR1SLC6A2HDAC8DPP4
SCHEMBL321221 0.86 SLC7A5 (0.61) SLC7A5TAAR1SLC6A2HDAC8DPP4
Pyruvate SCHEMBL4082845 0.85 SLC7A5 (0.53) SLC7A5TAAR1SLC6A2HDAC8DPP4
SCHEMBL23243815 0.85 SLC7A5 (0.46) SLC7A5DPP4ALPIPKMPTGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1727 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3333261-B1 HEXURONATE C4-EPIMERASE VARIANT WITH IMPROVED D-TAGATOSE PRODUCTION ACTIVITY, AND D-TAGATOSE PRODUCTION METHOD USING SAME CJ CHEILJEDANG CORP (KR) 2023-11-15 EP claimed
EP-3710594-B1 METHODS TO MEASURE FUNCTIONAL HETEROGENEITY AMONG SINGLE CELLS UNIV COLORADO REGENTS (US) 2023-07-19 EP claimed
EP-3911354-B1 AAV-MEDIATED GENE THERAPY RESTORING THE OTOFERLIN GENE PASTEUR INSTITUT (FR) 2023-07-19 EP claimed
CN-114377154-B X-ray fluorescence and fluorescence bimodal imaging probe based on synchrotron radiation light source, preparation method and application 中国科学院上海高等研究院 2023-07-07 CN claimed
US-20230105024-A1 Bifunctional C-Glycoside Glycosyltransferases and Application Thereof CAS CENTER FOR EXCELLENCE IN MOLECULAR PLANT SCIENCES (CN) 2023-04-06 US claimed
US-20230066984-A1 New Carbon Glycoside Glycosyltransferase and Use Thereof CAS CENTER FOR EXCELLENCE IN MOLECULAR PLANT SCIENCES (CN) 2023-03-02 US claimed
CN-115552013-A Modified micronucleus core proteins and their use in nucleic acid delivery 加总生物公司 2022-12-30 CN claimed
EP-4108777-A1 BIFUNCTIONAL C-GLYCOSIDE GLYCOSYLTRANSFERASES AND APPLICATION THEREOF CAS Center for Excellence in Molecular Plant Sciences (CN) 2022-12-28 EP claimed
US-20220396611-A1 FACTOR VIII CONSTRUCT SPUR THERAPEUTICS LIMITED (GB) 2022-12-15 US claimed
CN-114929735-A Factor VIII constructs 自由行疗法有限公司 2022-08-19 CN claimed
EP-0804484-A1 ANTIGENIC POLYPEPTIDE SEQUENCE OF FACTOR VIII, FRAGMENTS AND/OR EPITOPES THEREOF CROIX ROUGE DE BELGIQUE (BE) 1997-11-05 EP claimed
US-5674703-A CONSISTING OF PAPILLOMA VIRUS ORIGIN OF REPLICATION, FIRST PROMOTER TRANSCRIPTIONALLY LINKED TO DNA SEQUENCE, SECOND PROMOTER LINKED TO PAPILLOMA VIRUS E1 GENE SEQUENCE, THIRD PROMOTER LINKED TO PAPILLOMA VIRUS E2 GENE SEQUENCE BAYLOR COLLEGE OF MEDICINE 1997-10-07 US claimed
WO-1996002572-A2 ANTIGENIC POLYPEPTIDE SEQUENCE OF FACTOR VIII, FRAGMENTS AND/OR EPITOPES THEREOF CROIX-ROUGE DE BELGIQUE (BE) 1996-02-01 WO claimed
WO-1994012629-A1 EPISOMAL VECTORS FOR GENE THERAPY BAYLOR COLLEGE OF MEDICINE (US) 1994-06-09 WO claimed
EP-0375040-B1 Process for the preparation of retro-inverso peptides and new intermediates thereof SCLAVO SPA (IT) 1994-03-16 EP claimed
EP-0134631-B1 PEPTIDES, PHARMACEUTICAL COMPOSITIONS, GENES, VECTORS, HOST ORGANISMS, PROCESSES FOR THEIR PRODUCTION AND DIAGNOSTIC REAGENTS CELLTECH LIMITED (GB) 1991-04-03 EP claimed
EP-0089365-A4 New Dye or Fluorescent polymers and their use as labels in immunoassay systems. HENRY ROBERT P 1985-08-21 EP claimed
US-4452886-A Novel photon absorbing or emitting polymers and their use as reagents in immunoassay systems PHOTEST DIAGNOSTICS, INC. A CORPORATION OF DE 1984-06-05 US claimed
EP-0089365-A1 New Dye or Fluorescent polymers and their use as labels in immunoassay systems. PHOTEST DIAGNOSTICS, INC. (US) 1983-09-28 EP claimed
WO-1983001064-A1 NOVEL PHOTON ABSORBING OR EMITTING POLYMERS AND THEIR USE AS REAGENTS IN IMMUNOASSAY SYSTEMS HENRY, ROBERT, P. 1983-03-31 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230066984-A1 New Carbon Glycoside Glycosyltransferase and Use Thereof UGGT1, UGDH, UGCG SLC7A5 1880/4885TAAR1 4843/4885SLC6A2 1136/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.