Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | LRRK2 | Q5S007 | 4/20 | 0.39 |
| ▸ | HCRTR1 | O43613 | 3/20 | 0.38 |
| ▸ | HCRTR2 | O43614 | 3/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.37 |
| ▸ | BCAT1 | P54687 | 1/20 | 0.36 |
| ▸ | EGLN2 | Q96KS0 | 2/20 | 0.36 |
| ▸ | CASP6 | P55212 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 2/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.33 |
| ▸ | FEN1 | P39748 | 1/20 | 0.33 |
| ▸ | TDO2 | P48775 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1536988 | 0.83 | MAPK1 (0.47) | MAPK1HCRTR1HCRTR2SCN9AIDO1 | |
| SCHEMBL27928104 | 0.78 | SCN9A (0.41) | HCRTR1HCRTR2SCN9ABCAT1CASP6 | |
| SCHEMBL1868592 | 0.76 | SCN9A (0.40) | HCRTR1HCRTR2SCN9ACASP6IDO1 | |
| SCHEMBL30814370 | 0.74 | GRIA1 (0.43) | MAPK1LRRK2BCAT1ADORA2A | |
| SCHEMBL28856972 | 0.74 | GRIA1 (0.43) | MAPK1LRRK2BCAT1ADORA2A | |
| SCHEMBL5337879 | 0.73 | MAPK1 (0.40) | MAPK1HCRTR1HCRTR2SCN9A | |
| SCHEMBL30719203 | 0.72 | HTT (0.41) | LRRK2BCAT1EGLN2CASP6ADORA2A | |
| SCHEMBL26259974 | 0.72 | SCN9A (0.43) | SCN9ACASP6IDO1TDO2 | |
| SCHEMBL21596836 | 0.71 | LRRK2 (0.43) | LRRK2BCAT1EGLN2ADORA2A | |
| SCHEMBL30042177 | 0.71 | MAPK1 (0.42) | MAPK1LRRK2HCRTR1HCRTR2IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2054410-A2 | OXAZOLIDONE DERIVATIVES AS PR MODULATORS | Wyeth (US) | 2009-05-06 | — | — | EP | disclosed |
| WO-2008021331-A2 | OXAZOLIDONE DERIVATIVES AS PR MODULATORS | WYETH (US) | 2008-02-21 | — | — | WO | disclosed |