Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 1/20 | 0.40 |
| ▸ | MPL | P40238 | 3/20 | 0.39 |
| ▸ | CASP6 | P55212 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 5/20 | 0.36 |
| ▸ | TDO2 | P48775 | 3/20 | 0.35 |
| ▸ | METAP2 | P50579 | 4/20 | 0.34 |
| ▸ | METAP1 | P53582 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1800346 | 0.82 | ALDH1A1 (0.46) | SCN9AIDO1TDO2METAP2METAP1 | |
| SCHEMBL20723607 | 0.79 | TSHR (0.43) | SCN9AIDO1TDO2METAP2METAP1 | |
| Hydrochloric Acid SCHEMBL6765946 | 0.79 | ALDH1A1 (0.43) | SCN9AIDO1TDO2METAP2METAP1 | |
| Bromide SCHEMBL7959477 | 0.79 | ALDH1A1 (0.43) | SCN9AIDO1TDO2METAP2METAP1 | |
| SCHEMBL4082911 | 0.76 | MAPK1 (0.41) | SCN9ACASP6IDO1TDO2HCRTR1 | |
| SCHEMBL10151023 | 0.74 | MPL (0.50) | SCN9AMPLCASP6IDO1TDO2 | |
| SCHEMBL28363719 | 0.72 | CD44 (0.39) | SCN9AIDO1TDO2METAP2METAP1 | |
| SCHEMBL28360058 | 0.72 | SCN9A (0.37) | SCN9AIDO1TDO2METAP2METAP1 | |
| SCHEMBL8166926 | 0.72 | ALDH1A1 (0.50) | MPLKDM4ECYP3A4TSHRSMN1; SMN2 | |
| SCHEMBL14754342 | 0.71 | CASP6 (0.48) | SCN9ACASP6IDO1TDO2METAP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024227104-A1 | BIFUNCTIONAL COMPOUNDS FOR DEGRADING BRAF VIA UBIQUITIN PROTEOSOME PATHWAY | NURIX THERAPEUTICS, INC. (US) | 2024-10-31 | — | — | WO | disclosed |
| EP-2498608-A1 | BENZENE SULFONAMIDE THIAZOLE AND OXAZOLE COMPOUNDS | GlaxoSmithKline LLC (US) | 2012-09-19 | — | — | EP | disclosed |
| WO-2011059610-A1 | BENZENE SULFONAMIDE THIAZOLE AND OXAZOLE COMPOUNDS | GLAXOSMITHKLINE LLC (US) | 2011-05-19 | — | — | WO | disclosed |