Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | BCHE | P06276 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14104521 | 0.98 | SMN1; SMN2 (0.32) | SMN1; SMN2BCHEACHE | |
| Hydrochloric Acid SCHEMBL8350682 | 0.96 | BCHE (0.32) | SMN1; SMN2BCHEACHE | |
| SCHEMBL4081706 | 0.87 | — | — | |
| Sulfuric Acid SCHEMBL4085938 | 0.86 | SMN1; SMN2 (0.30) | SMN1; SMN2 | |
| SCHEMBL4091175 | 0.83 | BCHE (0.32) | BCHEACHE | |
| SCHEMBL4088097 | 0.77 | CYP2C9 (0.36) | SMN1; SMN2 | |
| SCHEMBL12863227 | 0.77 | TP53 (0.36) | SMN1; SMN2TP53 | |
| SCHEMBL8823189 | 0.76 | — | — | |
| Bromide SCHEMBL9190482 | 0.75 | TP53 (0.52) | SMN1; SMN2TP53 | |
| Bromide SCHEMBL4087944 | 0.73 | TRIM24 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2081543-A2 | BLEACHING AGENT COMPRISING PIPERIDONE/S AND IMIDAZOLE/S | Henkel AG & Co. KGaA (DE) | 2009-07-29 | — | — | EP | claimed |
| WO-2008095558-A2 | BLEACHING AGENT COMPRISING PIPERIDONE/S AND IMIDAZOLE/S | HENKEL AG & CO. KGAA (DE) | 2008-08-14 | — | — | WO | claimed |