Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRIM24 | O15164 | 1/20 | 0.30 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.30 |
| ▸ | CHRNA10 | Q9GZZ6 | 1/20 | 0.30 |
| ▸ | CHRNA9 | Q9UGM1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL739073 | 0.97 | TRIM24 (0.32) | TRIM24TRIM33CHRNA10CHRNA9 | |
| Hydrochloric Acid SCHEMBL7493640 | 0.95 | TRIM24 (0.30) | TRIM24TRIM33CHRNA10CHRNA9 | |
| Iodide SCHEMBL426332 | 0.95 | CHRNA10 (0.33) | TRIM24TRIM33CHRNA10CHRNA9 | |
| SCHEMBL4091649 | 0.85 | — | — | |
| Sulfuric Acid SCHEMBL4083513 | 0.83 | — | — | |
| SCHEMBL4083156 | 0.80 | — | — | |
| SCHEMBL10256575 | 0.78 | — | — | |
| Bromide SCHEMBL3741619 | 0.77 | CHRNA7 (0.33) | TRIM24TRIM33CHRNA10CHRNA9 | |
| SCHEMBL4078041 | 0.74 | CYP2C9 (0.38) | — | |
| Bromide SCHEMBL4082986 | 0.73 | SMN1; SMN2 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2081543-A2 | BLEACHING AGENT COMPRISING PIPERIDONE/S AND IMIDAZOLE/S | Henkel AG & Co. KGaA (DE) | 2009-07-29 | — | — | EP | claimed |
| WO-2008095558-A2 | BLEACHING AGENT COMPRISING PIPERIDONE/S AND IMIDAZOLE/S | HENKEL AG & CO. KGAA (DE) | 2008-08-14 | — | — | WO | claimed |