Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY6 | Q15077 | 3/20 | 0.39 |
| ▸ | P2RY14 | Q15391 | 2/20 | 0.39 |
| ▸ | NT5E | P21589 | 1/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | SCD | O00767 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | GHSR | Q92847 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.32 |
| ▸ | P2RY4 | P51582 | 1/20 | 0.32 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4083486 | 0.98 | P2RY6 (0.38) | P2RY6P2RY14NT5EABL1RIN1 | |
| SCHEMBL4078632 | 0.85 | NT5E (0.40) | P2RY6P2RY14NT5EMEN1KMT2A | |
| SCHEMBL4083482 | 0.83 | P2RY6 (0.39) | P2RY6P2RY14NT5EABL1RIN1 | |
| SCHEMBL4078638 | 0.83 | NT5E (0.38) | P2RY14NT5EALDH1A1GHSR | |
| SCHEMBL13722534 | 0.79 | P2RY6 (0.45) | P2RY6P2RY14NT5EABL1RIN1 | |
| SCHEMBL4075038 | 0.73 | NT5E (0.42) | P2RY6P2RY14NT5EMEN1KMT2A | |
| SCHEMBL13721996 | 0.72 | ABL1 (0.41) | P2RY6P2RY14NT5EABL1RIN1 | |
| SCHEMBL4075042 | 0.71 | NT5E (0.40) | P2RY6P2RY14NT5EP2RY2P2RY4 | |
| SCHEMBL4074822 | 0.71 | P2RY6 (0.31) | P2RY6P2RY14NT5EABL1RIN1 | |
| SCHEMBL4082385 | 0.70 | P2RY6 (0.43) | P2RY6P2RY14NT5EABL1RIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7569686-B1 | Compounds and methods for synthesis of bicyclic nucleic acid analogs | ISIS PHARMACEUTICALS, INC. (US) | 2009-08-04 | — | — | US | disclosed |