SCHEMBL4083630

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4283385	0.96	EPHX2 (0.46)	EPHX2ARKCNH2SIGMAR1SIRT2
	SCHEMBL3978599	0.90	FABP1 (0.50)	THRBFAAHFABP1PRSS1ALDH1A1
	SCHEMBL3978333	0.90	FABP1 (0.50)	THRBFAAHFABP1PRSS1ALDH1A1
	SCHEMBL3976349	0.90	FABP1 (0.50)	THRBFAAHFABP1PRSS1ALDH1A1
	SCHEMBL3975905	0.89	FABP1 (0.48)	THRBFAAHKMT2AMEN1FABP1
	SCHEMBL4979323	0.88	HPGD (0.50)	SIGMAR1THRBFAAHKMT2AMEN1
	SCHEMBL4079774	0.88	MAPT (0.45)	SIRT2THRBFAAHKMT2AMEN1
	SCHEMBL3978011	0.88	CYP1A2 (0.50)	SIRT2THRBFAAHKMT2AMEN1
	SCHEMBL4080746	0.88	SIRT2 (0.41)	EPHX2SIRT2CRHBPCRHR2KMT2A
	SCHEMBL3975168	0.86	F2 (0.48)	THRBFAAHKMT2AMEN1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.