SCHEMBL4283385

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4083630	0.96	EPHX2 (0.43)	EPHX2ARKCNH2SIGMAR1THRB
	SCHEMBL3974860	0.89	ALDH1A1 (0.51)	THRBSIRT2KMT2ANPC1RAB9A
	SCHEMBL3978614	0.89	ALDH1A1 (0.51)	THRBSIRT2KMT2ANPC1RAB9A
	SCHEMBL3977061	0.89	ALDH1A1 (0.51)	THRBSIRT2KMT2ANPC1RAB9A
	SCHEMBL3973689	0.88	KMT2A (0.48)	EPHX2THRBSIRT2FAAHKMT2A
	SCHEMBL3973757	0.88	ALDH1A1 (0.53)	THRBSIRT2FAAHKMT2ANPC1
	SCHEMBL3984003	0.87	ALDH1A1 (0.50)	THRBFAAHPRSS1
	SCHEMBL4092320	0.87	HPGD (0.53)	ARKCNH2SIGMAR1THRBFAAH
	SCHEMBL3980364	0.87	MAPT (0.47)	THRBSIRT2FAAHKMT2AMEN1
	SCHEMBL5053666	0.86	SMN1; SMN2 (0.49)	EPHX2CRHBPCRHR2KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.