Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 12/20 | 0.55 |
| ▸ | SPR | P35270 | 1/20 | 0.44 |
| ▸ | NAMPT | P43490 | 1/20 | 0.43 |
| ▸ | RORC | P51449 | 4/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MMP13 | P45452 | 1/20 | 0.38 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL349688 | 0.90 | HSD11B1 (0.51) | HSD11B1SPRNAMPTRORCHDAC4 | |
| SCHEMBL351480 | 0.78 | HSD11B1 (0.65) | HSD11B1SPR | |
| SCHEMBL350846 | 0.73 | HSD11B1 (0.59) | HSD11B1 | |
| SCHEMBL350847 | 0.73 | HSD11B1 (0.59) | HSD11B1 | |
| SCHEMBL350421 | 0.73 | HSD11B1 (0.59) | HSD11B1 | |
| SCHEMBL350420 | 0.73 | HSD11B1 (0.59) | HSD11B1 | |
| SCHEMBL5901385 | 0.73 | HSD11B1 (0.57) | HSD11B1SPRNAMPTADAMTS5 | |
| SCHEMBL350061 | 0.72 | HSD11B1 (0.82) | HSD11B1SPR | |
| SCHEMBL350402 | 0.71 | HSD11B1 (1.00) | HSD11B1SPR | |
| SCHEMBL4965635 | 0.71 | SMN1; SMN2 (0.46) | RORCMMP13ADAMTS5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2963021-A1 | AMIDO COMPOUNDS AND THEIR USE AS PHARMACEUTICALS | Incyte Holdings Corporation (US) | 2016-01-06 | — | — | EP | claimed |
| EP-2963021-A1 | AMIDO COMPOUNDS AND THEIR USE AS PHARMACEUTICALS | Incyte Holdings Corporation (US) | 2016-01-06 | — | — | EP | disclosed |
| EP-1756063-A4 | AMIDO COMPOUNDS AND THEIR USE AS PHARMACEUTICALS | INCYTE CORP (US) | 2009-03-25 | — | — | EP | disclosed |
| EP-1756063-A1 | AMIDO COMPOUNDS AND THEIR USE AS PHARMACEUTICALS | Incyte Corporation (US) | 2007-02-28 | — | — | EP | disclosed |
| WO-2005110992-A1 | AMIDO COMPOUNDS AND THEIR USE AS PHARMACEUTICALS | INCYTE CORPORATION (US) | 2005-11-24 | — | — | WO | disclosed |