Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 6/20 | 0.53 |
| ▸ | PRMT1 | Q99873 | 2/20 | 0.50 |
| ▸ | NT5E | P21589 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | DNASE1L3 | Q13609 | 1/20 | 0.37 |
| ▸ | SUMO2 | P61956 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4084052 | 1.00 | ENPP2 (0.53) | ENPP2PRMT1NT5EMEN1KMT2A | |
| SCHEMBL4084068 | 0.95 | ENPP2 (0.51) | ENPP2PRMT1NT5EMEN1KMT2A | |
| SCHEMBL4083203 | 0.87 | PRMT1 (0.47) | ENPP2PRMT1NT5EMEN1KMT2A | |
| SCHEMBL4083210 | 0.86 | PRMT1 (0.46) | ENPP2PRMT1NT5EMEN1KMT2A | |
| SCHEMBL11656372 | 0.83 | ENPP2 (0.56) | ENPP2PRMT1NT5EMEN1KMT2A | |
| SCHEMBL11656374 | 0.83 | ENPP2 (0.56) | ENPP2PRMT1NT5EMEN1KMT2A | |
| SCHEMBL4083221 | 0.82 | PRMT1 (0.46) | ENPP2PRMT1NT5EMEN1KMT2A | |
| SCHEMBL14026027 | 0.81 | ENPP2 (0.49) | ENPP2PRMT1MEN1KMT2AHTT | |
| SCHEMBL11320185 | 0.81 | ENPP2 (0.49) | ENPP2MEN1KMT2AHTTCYP1A2 | |
| SCHEMBL24279857 | 0.81 | ENPP2 (0.62) | ENPP2PRMT1MEN1KMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7531009-B2 | 6-azo-5,5′-dihydroxy-7,7′-disulfo-2-2′ dinaphthylamine derivatives | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2009-05-12 | — | — | US | disclosed |
| US-20080196180-A1 | 6-Azo-5,5'-Dihydroxy-7,7'-Disulfo-2-2' Dinaphthylamine Derivatives | CIBA SPECIALTY CHEMICALS CORP. | 2008-08-21 | — | — | US | disclosed |
| EP-1838788-A2 | 6-AZO-5,5'-DIHYDROXY-7,7'-DISULFO-2,2'-DINAPHTHYLAMINE DERIVATIVES | Ciba Specialty Chemicals Holding Inc. (CH) | 2007-10-03 | — | — | EP | disclosed |
| WO-2006077189-A2 | 6-AZO-5,5'-DIHYDROXY-7,7'-DISULFO-2,2'-DINAPHTHYLAMINE DERIVATIVES | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2006-07-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080196180-A1 | 6-Azo-5,5'-Dihydroxy-7,7'-Disulfo-2-2' Dinaphthylamine Derivatives | H1-5, DHODH, DDT | ENPP2 1644/4885PRMT1 2442/4885NT5E 43/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.