Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 7/20 | 0.71 |
| ▸ | CNR2 | P34972 | 1/20 | 0.48 |
| ▸ | PTPRC | P08575 | 2/20 | 0.44 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.44 |
| ▸ | PTPRB | P23467 | 2/20 | 0.44 |
| ▸ | PTPRE | P23469 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | RAB7A | P51149 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.40 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.39 |
| ▸ | GABRP | O00591 | 1/20 | 0.38 |
| ▸ | GABRD | O14764 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4086551 | 0.85 | KMT2A (0.55) | PTPN1CNR2KMT2AALDH1A1MAPT | |
| SCHEMBL4089515 | 0.84 | CNR2 (0.71) | PTPN1CNR2POLB | |
| SCHEMBL4090461 | 0.81 | CNR2 (0.70) | PTPN1CNR2PTPRCPTPN2PTPRB | |
| SCHEMBL4144598 | 0.80 | PTPN1 (0.72) | PTPN1PTPRCPTPN2PTPRBPTPRE | |
| SCHEMBL21603822 | 0.79 | PTPN1 (0.61) | PTPN1PTPRCPTPN2PTPRBPTPRE | |
| SCHEMBL4091622 | 0.79 | PTPN1 (0.63) | PTPN1PTPRCPTPN2PTPRBPTPRE | |
| SCHEMBL4086799 | 0.79 | PTPN1 (0.63) | PTPN1PTPRCPTPN2PTPRBPTPRE | |
| SCHEMBL5453513 | 0.77 | FLT3 (0.62) | PTPN1KMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL5458434 | 0.76 | PTPN1 (0.55) | PTPN1KMT2AMEN1NPC1ALDH1A1 | |
| SCHEMBL4079889 | 0.76 | PTPN1 (0.66) | PTPN1CNR2PTPRCPTPN2PTPRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8338623-B2 | N-{3-[(2,5-dimethylmorpholin-4-yl)carbonyl]-4,7-dihydro-5H-thieno[2,3-c]pyran-2-yl}hexahydro-2,5-methanopentalene-3a(1H)-carboxamide; CB2 receptors ligand; antiinflammatory, analgesic agent; autoimmune diseases; neuroprotectants | ABBVIE INC. (US) | 2012-12-25 | — | — | US | disclosed |
| US-20090018114-A1 | NOVEL COMPOUNDS AS CANNABINOID RECEPTOR LIGANDS | ABBOTT LABORATORIES (US) | 2009-01-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090018114-A1 | NOVEL COMPOUNDS AS CANNABINOID RECEPTOR LIGANDS | CNR1, CNR2, GPR18 | PTPN1 2348/4885CNR2 2/4885PTPRC 1716/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.