Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA5 | P22460 | 5/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | KCNE1 | P15382 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | SCN1A | P35498 | 1/20 | 0.36 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.36 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | SUMO3 | P55854 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4543244 | 0.80 | SLC6A2 (0.44) | KCNA5KCNH2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL11367296 | 0.80 | KCNA5 (0.42) | KCNA5KCNH2SLC2A1SLC6A2SLC6A4 | |
| SCHEMBL10619146 | 0.78 | SLC6A2 (0.43) | KCNA5SLC6A2SLC6A4SLC6A3TSHR | |
| SCHEMBL7139371 | 0.73 | SCN8A (0.47) | KCNA5KCNH2SLC2A1SLC6A2SLC6A4 | |
| SCHEMBL3297741 | 0.73 | SMN1; SMN2 (0.43) | TSHRALDH1A1SMN1; SMN2KDM4EHTT | |
| SCHEMBL10970051 | 0.71 | SLC6A2 (0.36) | KCNA5SLC6A2SLC6A4SLC6A3TSHR | |
| SCHEMBL9791901 | 0.71 | SLC6A2 (0.33) | KCNA5SLC6A2SLC6A4SLC6A3TSHR | |
| SCHEMBL27965975 | 0.70 | SLC6A2 (0.41) | KCNA5KCNH2SLC2A1SLC6A2SLC6A4 | |
| SCHEMBL6160196 | 0.70 | SLC6A2 (0.48) | KCNA5KCNH2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL11800360 | 0.70 | SLC6A2 (0.48) | KCNA5KCNH2SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7579459-B2 | Activator bound solid supports for nucleic acid synthesis via the phosphoramidite approach | NGO NAM Q | 2009-08-25 | — | — | US | disclosed |
| US-20070135626-A1 | Activator bound solid supports for nucleic acid synthesis via the phosphoramidite approach | CTGEN, INC (US) | 2007-06-14 | — | — | US | disclosed |