Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 2/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.48 |
| ▸ | KCNA5 | P22460 | 5/20 | 0.42 |
| ▸ | KCNE1 | P15382 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CCR1 | P32246 | 1/20 | 0.39 |
| ▸ | CCR5 | P51681 | 1/20 | 0.39 |
| ▸ | CCR8 | P51685 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11800360 | 0.82 | SLC6A2 (0.48) | SLC6A2SLC6A4SLC6A3KCNA5KCNE1 | |
| SCHEMBL3096488 | 0.80 | SLC6A2 (0.56) | SLC6A2SLC6A4SLC6A3KCNA5KCNE1 | |
| SCHEMBL10569701 | 0.79 | SLC6A2 (0.57) | SLC6A2SLC6A4SLC6A3KCNA5KCNE1 | |
| SCHEMBL29029215 | 0.79 | SLC6A2 (0.57) | SLC6A2SLC6A4SLC6A3KCNA5KCNE1 | |
| SCHEMBL4954290 | 0.78 | SLC6A2 (0.45) | SLC6A2SLC6A4SLC6A3KCNA5KCNE1 | |
| SCHEMBL11034374 | 0.78 | SLC6A2 (0.45) | SLC6A2SLC6A4SLC6A3KCNA5KCNE1 | |
| SCHEMBL4759333 | 0.78 | SLC6A2 (0.45) | SLC6A2SLC6A4SLC6A3KCNA5KCNE1 | |
| SCHEMBL10945061 | 0.78 | SLC6A2 (0.45) | SLC6A2SLC6A4SLC6A3KCNA5KCNE1 | |
| SCHEMBL21742323 | 0.78 | SLC6A2 (0.45) | SLC6A2SLC6A4SLC6A3KCNA5KCNE1 | |
| SCHEMBL1385556 | 0.78 | SLC6A3 (0.45) | SLC6A2SLC6A4SLC6A3KCNA5KCNE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1505156-B1 | Process for the enantioselective preparation of secondary alcohols by lipase catalysed solvolysis of the corresponding acetoacetic acid ester | CONSORTIUM ELEKTROCHEM IND (DE) | 2005-12-07 | — | — | EP | disclosed |
| EP-1505156-A1 | Process for the enantioselective preparation of secondary alcohols by lipase catalysed solvolysis of the corresponding acetoacetic acid ester | Consortium für elektrochemische Industrie GmbH (DE) | 2005-02-09 | — | — | EP | disclosed |