Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 20/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5553840 | 0.82 | P2RX7 (0.81) | P2RX7 | |
| SCHEMBL5549317 | 0.82 | P2RX7 (1.00) | P2RX7 | |
| SCHEMBL5549342 | 0.82 | P2RX7 (1.00) | P2RX7 | |
| Hydrochloric Acid SCHEMBL5549341 | 0.81 | P2RX7 (0.98) | P2RX7 | |
| Hydrochloric Acid SCHEMBL5553877 | 0.81 | P2RX7 (0.98) | P2RX7 | |
| SCHEMBL4129731 | 0.81 | P2RX7 (0.73) | P2RX7 | |
| SCHEMBL7571588 | 0.80 | P2RX7 (1.00) | P2RX7 | |
| SCHEMBL7555635 | 0.80 | P2RX7 (0.72) | P2RX7 | |
| SCHEMBL6574267 | 0.79 | P2RX7 (1.00) | P2RX7 | |
| SCHEMBL5553045 | 0.79 | P2RX7 (0.75) | P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2059497-A1 | PROCESS FOR PREPARING N-METHYLADAMANTYL DERIVATIVES BY A PALLADIUM CATALYSED COUPLING REACTION FOLLOWED BY REDUCTIVE AMINATION | AstraZeneca AB (SE) | 2009-05-20 | — | — | EP | disclosed |
| WO-2008030160-A1 | PROCESS FOR PREPARING N-METHYLADAMANTYL DERIVATIVES BY A PALLADIUM CATALYSED COUPLING REACTION FOLLOWED BY REDUCTIVE AMINATION | ASTRAZENECA AB (SE) | 2008-03-13 | — | — | WO | disclosed |