SCHEMBL4085453

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4090304	0.85	LMNA (0.43)	HSP90AB1ALDH1A1LMNAKMT2AMEN1
	SCHEMBL4091826	0.85	HSP90AA1 (0.46)	HSP90AB1ALDH1A1HSP90AA1KDM4EPOLB
	SCHEMBL4096157	0.84	HSP90AB1 (0.46)	HSP90AB1LMNAHPGDHSP90AA1POLB
	SCHEMBL4085460	0.83	HSP90AB1 (0.44)	HSP90AB1HPGDHSP90AA1POLBMAPK1
	SCHEMBL4086622	0.83	HSP90AA1 (0.48)	HSP90AB1HSP90AA1KDM4ETP53MAPK1
	SCHEMBL4090231	0.82	HSP90AB1 (0.41)	HSP90AB1HSP90AA1KDM4E
	SCHEMBL4091813	0.82	ATM (0.43)	HSP90AB1ALDH1A1LMNARAB9AKMT2A
	SCHEMBL4096191	0.80	HSP90AB1 (0.43)	HSP90AB1ALDH1A1KMT2ANPSR1SMN1; SMN2
	SCHEMBL4094051	0.78	HSP90AB1 (0.47)	HSP90AB1RAB9AHSP90AA1CYP2C19POLB
	SCHEMBL4093798	0.78	HSP90AB1 (0.47)	HSP90AB1ALDH1A1LMNAGAAHSP90AA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.