Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 11/20 | 0.42 |
| ▸ | CHRM2 known ✓ | P08172 | 1/20 | 0.39 |
| ▸ | CHRM4 known ✓ | P08173 | 1/20 | 0.39 |
| ▸ | CHRM5 known ✓ | P08912 | 1/20 | 0.39 |
| ▸ | CHRM1 known ✓ | P11229 | 1/20 | 0.39 |
| ▸ | CHRM3 known ✓ | P20309 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.62 |
| ▸ | TP53 | P04637 | 1/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.62 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 1/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.62 |
| ▸ | HTT | P42858 | 3/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | NPC1 | O15118 | 1/20 | 0.60 |
| ▸ | RAB9A | P51151 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3211312 | 0.97 | MEN1 (0.65) | KMT2AMEN1TP53CYP1A2CYP2D6 | |
| Hydrochloric Acid SCHEMBL4081103 | 0.94 | MEN1 (0.62) | KMT2AMEN1TP53CYP1A2CYP2D6 | |
| Fluoride Ion SCHEMBL11050205 | 0.94 | MEN1 (0.62) | KMT2AMEN1TP53CYP1A2CYP2D6 | |
| Bromide SCHEMBL21750926 | 0.91 | KMT2A (0.54) | KMT2AMEN1TP53CYP1A2CYP2D6 | |
| SCHEMBL3204759 | 0.90 | MEN1 (0.58) | KMT2AMEN1TP53CYP1A2CYP2D6 | |
| SCHEMBL3212692 | 0.87 | MEN1 (0.56) | KMT2AMEN1TP53CYP1A2CYP2D6 | |
| SCHEMBL16843092 | 0.87 | MEN1 (0.56) | KMT2AMEN1TP53CYP1A2CYP2D6 | |
| SCHEMBL8080641 | 0.87 | TP53 (0.56) | KMT2AMEN1TP53CYP1A2CYP2D6 | |
| Iodide SCHEMBL8080283 | 0.85 | KDM4E (0.57) | KMT2AMEN1TP53CYP1A2CYP2D6 | |
| Bromide SCHEMBL28311092 | 0.85 | ACHE (0.54) | KMT2AMEN1TP53CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180371310-A1 | DYNAMIC RESPONSE COMPONENTS WITH AESTHETIC PROPERTIES | FUNDACIÓN CIDETEC (ES) | 2018-12-27 | — | — | US | disclosed |
| EP-3395927-A1 | DYNAMIC RESPONSE COMPONENTS WITH AESTHETIC PROPERTIES | Fundacion Cidetec (ES) | 2018-10-31 | — | — | EP | disclosed |
| US-7500895-B2 | Patterned substrate, electro-optical device, and method for manufacturing an electro-optical device | SEIKO EPSON CORPORATION (JP) | 2009-03-10 | — | — | US | disclosed |
| US-20060127563-A1 | Patterned substrate, electro-optical device, and method for manufacturing an electro-optical device | SEIKO EPSON CORPORATION (JP) | 2006-06-15 | — | — | US | disclosed |
| US-20050287392-A1 | Organic electroluminescent device, method for producing the same, and electronic apparatus | SEIKO EPSON CORPORATION (JP) | 2005-12-29 | — | — | US | disclosed |