SCHEMBL4086352

SCHEMBL4086352

C=COC(=O)c1cc(C(=O)O)ccc1C(=O)O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.50
HSD17B10 Q99714 2/20 0.43
CDC25A P30304 1/20 0.43
CDC25B P30305 1/20 0.43
POLB P06746 4/20 0.42
L3MBTL1 Q9Y468 3/20 0.42
TDP1 Q9NUW8 2/20 0.42
RAB9A P51151 2/20 0.40
LMNA P02545 1/20 0.40
MYC P01106 1/20 0.39
APEX1 P27695 1/20 0.38
CTDSP1 Q9GZU7 1/20 0.38
PTPN1 P18031 1/20 0.38
ACE2 Q9BYF1 1/20 0.37
CA12 O43570 2/20 0.37
CA1 P00915 2/20 0.37
CA2 P00918 2/20 0.37
CA4 P22748 2/20 0.37
CA6 P23280 2/20 0.37
CA7 P43166 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5360289 0.95 KDM4E (0.43) KDM4EHSD17B10CDC25ACDC25BPOLB
SCHEMBL27474070 0.93 KDM4E (0.46) KDM4EHSD17B10CDC25ACDC25BPOLB
SCHEMBL13538884 0.86 HSD17B10 (0.43) KDM4EHSD17B10CDC25ACDC25BPOLB
SCHEMBL4086350 0.84 ALDH1A1 (0.37) KDM4EHSD17B10CDC25ACDC25BPOLB
SCHEMBL29402845 0.84 ALDH1A1 (0.37) KDM4EHSD17B10CDC25ACDC25BPOLB
SCHEMBL27262563 0.83 KDM4E (0.47) KDM4EHSD17B10CDC25ACDC25BPOLB
SCHEMBL13538983 0.81 TSHR (0.34) KDM4EHSD17B10CDC25ACDC25BPTPN1
SCHEMBL220302 0.81 TSHR (0.34) KDM4EHSD17B10CDC25ACDC25BPTPN1
SCHEMBL9255617 0.81 ELANE (0.40) KDM4EPOLBL3MBTL1TDP1RAB9A
SCHEMBL625194 0.79 CYP3A4 (0.56) KDM4EHSD17B10CDC25ACDC25BPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2061523-A2 ABSORBENT ARTICLES COMPRISING SUPERABSORBENT POLYMERS HAVING SUPERIOR PROPERTIES Kimberly-Clark Worldwide, Inc. (US) 2009-05-27 EP disclosed
WO-2008027489-A2 ABSORBENT ARTICLES COMPRISING SUPERABSORBENT POLYMERS HAVING SUPERIOR PROPERTIES KIMBERLY-CLARK WORLDWIDE, INC. (US) 2008-03-06 WO disclosed
EP-1230026-A1 ION EXCHANGE RESINS AND METHODS OF MAKING THE SAME BASF AKTIENGESELLSCHAFT (DE) 2002-08-14 EP disclosed
WO-2001030495-A1 ION EXCHANGE RESINS AND METHODS OF MAKING THE SAME BASF AKTIENGESELLSCHAFT (DE) 2001-05-03 WO disclosed
EP-0259172-B1 COATING COMPOSITION COURTAULDS COATINGS (HOLDINGS) LIMITED (GB) 1992-09-16 EP disclosed
US-4826921-A Coating composition INTERNATIONAL PAINT PUBLIC LIMITED COMPANY (GB) 1989-05-02 US disclosed