SCHEMBL4086569

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3984003	0.95	ALDH1A1 (0.50)	HDAC1HDAC2HDAC3HDAC4HDAC7
	SCHEMBL3974860	0.92	ALDH1A1 (0.51)	ALDH1A1HTTTP53TYRTSHR
	SCHEMBL3978614	0.92	ALDH1A1 (0.51)	ALDH1A1HTTTP53TYRTSHR
	SCHEMBL3977061	0.92	ALDH1A1 (0.51)	ALDH1A1HTTTP53TYRTSHR
	SCHEMBL3973757	0.90	ALDH1A1 (0.53)	ALDH1A1HTTCYP3A4CYP2D6CYP2C9
	SCHEMBL3978152	0.88	SIRT2 (0.48)	ALDH1A1HTTTP53TYRTSHR
	SCHEMBL3977087	0.88	PRSS1 (0.54)	ALDH1A1HTTCYP3A4CYP2D6CYP2C9
	SCHEMBL3425886	0.87	ALDH1A1 (0.60)	HDAC1HDAC2HDAC3HDAC4HDAC7
	SCHEMBL3976068	0.87	HDAC1 (0.50)	HDAC1HDAC2HDAC3HDAC4HDAC7
	SCHEMBL3982862	0.86	SIRT2 (0.55)	ALDH1A1HTTPOLBTP53TYR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.