D-Alanine

D-Alanine

SCHEMBL4086747

CC(=O)N(C(C)=O)[C@@H](CCCCN)C(=O)O.C[C@@H](N)C(=O)O.C[C@@H](N)C(=O)O

nearest known ligand 0.49

Full drug profile on Sugi Atlas →

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
GSR P00390 1/20 0.47
CPB2 Q96IY4 5/20 0.44
RNPEP Q9H4A4 1/20 0.42
GABRR1 P24046 2/20 0.41
LTA4H P09960 1/20 0.41
FOLH1 Q04609 1/20 0.34
GRIK1 P39086 1/20 0.33
SLC1A2 P43004 1/20 0.33
SLC1A1 P43005 1/20 0.33
GRIK2 Q13002 1/20 0.33
PAOX Q6QHF9 1/20 0.33
ITGB3 P05106 1/20 0.33
ITGA2B P08514 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Alanine SCHEMBL28591585 1.00 GSR (0.47) GSRCPB2RNPEPGABRR1LTA4H
SCHEMBL7593236 0.93 CPB2 (0.49) GSRCPB2RNPEPGABRR1FOLH1
SCHEMBL7593232 0.93 CPB2 (0.49) GSRCPB2RNPEPGABRR1FOLH1
SCHEMBL8200953 0.91 CPB2 (0.51) GSRCPB2RNPEPGABRR1FOLH1
SCHEMBL4727761 0.88 GABRR1 (0.43) GSRCPB2RNPEPGABRR1FOLH1
SCHEMBL4727762 0.88 GABRR1 (0.43) GSRCPB2RNPEPGABRR1FOLH1
SCHEMBL19742925 0.88 GABRR1 (0.43) GSRCPB2RNPEPGABRR1FOLH1
SCHEMBL4299117 0.86 GSR (0.38) GSRCPB2RNPEPGABRR1LTA4H
SCHEMBL29689829 0.84 GSR (0.42) GSRCPB2RNPEPGABRR1LTA4H
D-Alanine SCHEMBL5702871 0.84 GSR (0.39) GSRCPB2RNPEPGABRR1LTA4H

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230158101-A1 GLYCOPEPTIDE COMPOSITIONS HIKMA PHARMACEUTICALS USA INC. 2023-05-25 US disclosed
US-11628200-B2 Glycopeptide compositions XELLIA PHARMACEUTICALS APS (DK) 2023-04-18 US disclosed
EP-4147710-A1 GLYCOPEPTIDE COMPOSITIONS IN SOLUTION Xellia Pharmaceuticals ApS (DK) 2023-03-15 EP disclosed
US-11517609-B2 Glycopeptide compositions XELLIA PHARMACEUTICALS APS (DK) 2022-12-06 US disclosed
US-11168077-B2 Molecular rotor-based D-amino acids as tools for imaging peptidoglycan biosynthesis INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) 2021-11-09 US disclosed
US-20210220433-A1 Glycopeptide Compositions XELLIA PHARMACEUTICALS APS (DK) 2021-07-22 US disclosed
EP-3834837-A1 GLYCOPEPTIDE COMPOSITIONS Xellia Pharmaceuticals ApS (DK) 2021-06-16 EP disclosed
US-11000567-B2 Glycopeptide compositions XELLIA PHARMACEUTICALS APS 2021-05-11 US disclosed
US-20210047308-A1 MOLECULAR ROTOR-BASED D-AMINO ACIDS AS TOOLS FOR IMAGING PEPTIDOGLYCAN BIOSYNTHESIS INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) 2021-02-18 US disclosed
EP-3542812-B1 GLYCOPEPTIDE COMPOSITIONS XELLIA PHARMACEUTICALS APS (DK) 2021-01-13 EP disclosed
US-20170348385-A1 GLYCOPEPTIDE COMPOSITIONS HIKMA PHARMACEUTICALS USA INC. 2017-12-07 US disclosed
EP-3215173-A1 GLYCOPEPTIDE COMPOSITIONS Xellia Pharmaceuticals ApS (DK) 2017-09-13 EP disclosed
WO-2016071495-A1 GLYCOPEPTIDE COMPOSITIONS XELLIA PHARMACEUTICALS APS (DK) 2016-05-12 WO disclosed
US-7556932-B2 Particle based homogeneous assays using capillary electrophoresis with laser-induced fluorescence detection BECKMAN COULTER, INC. (US) 2009-07-07 US disclosed
US-20070259338-A1 Detection of preferential particles in sample; provide sensitized particles, incubate with sample, expose to capillary electrophoresis, determine concentration of particles in sample BECKMAN COULTER, INC. (US) 2007-11-08 US disclosed
US-7179658-B2 Particle based homogeneous assays using capillary electrophoresis with laser-induced fluorescence detection BECKMAN COULTER, INC. (US) 2007-02-20 US disclosed
EP-1432987-A4 PARTICLE BASED HOMOGENEOUS ASSAYS USING CAPILLARY ELECTROPHORESIS WITH LASER-INDUCED FLUORESCENCE DETECTION BECKMAN COULTER INC (US) 2005-04-06 EP disclosed
EP-1432987-A2 PARTICLE BASED HOMOGENEOUS ASSAYS USING CAPILLARY ELECTROPHORESIS WITH LASER-INDUCED FLUORESCENCE DETECTION Beckman Coulter, Inc. (US) 2004-06-30 EP disclosed
WO-2003023353-A2 PARTICLE BASED HOMOGENEOUS ASSAYS USING CAPILLARY ELECTROPHORESIS WITH LASER-INDUCED FLUORESCENCE DETECTION BECKMAN COULTER, INC. (US) 2003-03-20 WO disclosed
US-20030054569-A1 Particle based homogeneous assays using capillary electrophoresis with laser-induced fluorescence detection BECKMAN COULTER, INC. 2003-03-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11517609-B2 Glycopeptide compositions ASNS, B3GNT2, OGT GSR 2714/4885CPB2 1171/4885RNPEP 63/4885
US-11000567-B2 Glycopeptide compositions ASNS, B3GNT2, OGT GSR 2714/4885CPB2 1171/4885RNPEP 63/4885
US-20230158101-A1 GLYCOPEPTIDE COMPOSITIONS ASNS, OGT, B3GNT2 GSR 3752/4885CPB2 1397/4885RNPEP 69/4885
US-20210220433-A1 Glycopeptide Compositions ASNS, B3GNT2, OGT GSR 2714/4885CPB2 1171/4885RNPEP 63/4885
US-11628200-B2 Glycopeptide compositions ASNS, B3GNT2, OGT GSR 2714/4885CPB2 1171/4885RNPEP 63/4885
US-20170348385-A1 GLYCOPEPTIDE COMPOSITIONS ASNS, B3GNT2, OGT GSR 2714/4885CPB2 1171/4885RNPEP 63/4885
US-11168077-B2 Molecular rotor-based D-amino acids as tools for imaging peptidoglycan biosynthesis DDOST, DAD1, DAO GSR 2480/4885CPB2 1303/4885RNPEP 266/4885
US-20210047308-A1 MOLECULAR ROTOR-BASED D-AMINO ACIDS AS TOOLS FOR IMAGING PEPTIDOGLYCAN BIOSYNTHESIS DDOST, DAD1, DAO GSR 2480/4885CPB2 1303/4885RNPEP 266/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.