Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 19/20 | 0.63 |
| ▸ | GIPR | P48546 | 4/20 | 0.63 |
| ▸ | GLP1R | P43220 | 2/20 | 0.63 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.61 |
| ▸ | ADCY6 | O43306 | 2/20 | 0.59 |
| ▸ | ADCY3 | O60266 | 2/20 | 0.59 |
| ▸ | ADCY9 | O60503 | 2/20 | 0.59 |
| ▸ | ADCY5 | O95622 | 2/20 | 0.59 |
| ▸ | ADCY8 | P40145 | 2/20 | 0.59 |
| ▸ | ADCY7 | P51828 | 2/20 | 0.59 |
| ▸ | ADCY2 | Q08462 | 2/20 | 0.59 |
| ▸ | ADCY1 | Q08828 | 2/20 | 0.59 |
| ▸ | ADCY4 | Q8NFM4 | 2/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2663053 | 0.93 | TRPV1 (0.62) | GCGRGIPRGLP1RTRPV1ADCY6 | |
| SCHEMBL6190356 | 0.88 | GCGR (0.61) | GCGRGIPRGLP1RTRPV1ADCY6 | |
| SCHEMBL2663302 | 0.87 | GCGR (0.66) | GCGRGIPRGLP1RADCY6ADCY3 | |
| SCHEMBL2663548 | 0.86 | GCGR (0.56) | GCGRGIPRGLP1R | |
| SCHEMBL2663093 | 0.84 | GCGR (0.72) | GCGRGIPRGLP1RADCY6ADCY3 | |
| SCHEMBL2663018 | 0.83 | TRPV1 (0.61) | GCGRGIPRGLP1RTRPV1ADCY6 | |
| SCHEMBL2663091 | 0.82 | GCGR (0.73) | GCGRGIPRGLP1RADCY6ADCY3 | |
| SCHEMBL4086425 | 0.82 | GCGR (0.90) | GCGRGIPRGLP1RADCY6ADCY3 | |
| SCHEMBL9072760 | 0.81 | GCGR (0.82) | GCGRGIPRGLP1RADCY6ADCY3 | |
| SCHEMBL4092836 | 0.81 | GCGR (0.62) | GCGRGIPRGLP1RADCY6ADCY3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090143592-A1 | Glucagon Antagonists/Inverse Agonists | NOVO NORDISK A/S (DK) | 2009-06-04 | — | — | US | disclosed |
| US-20090143592-A1 | Glucagon Antagonists/Inverse Agonists | NOVO NORDISK A/S (DK) | 2009-06-04 | — | — | US | disclosed |
| EP-1183229-B1 | GLUCAGON ANTAGONISTS/INVERSE AGONISTS | NOVO NORDISK AS (DK) | 2005-10-26 | — | — | EP | disclosed |
| US-6503949-B1 | Treating Type 2 diabetes, hyperglycemia, impaired glucose tolerance or obesity | NORO NORDISK A/S (DK) | 2003-01-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090143592-A1 | Glucagon Antagonists/Inverse Agonists | GLP1R, GPR119, GCGR | GCGR 3/4885GIPR 4/4885GLP1R 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.